Literature DB >> 33972566

Mutations as Levy flights.

Dario A Leon1,2, Augusto Gonzalez3,4.   

Abstract

Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two components: random single-base substitutions and large DNA rearrangements. From the data, we get estimations for the time rates of both events and the size distribution function of large rearrangements.

Entities:  

Year:  2021        PMID: 33972566     DOI: 10.1038/s41598-021-88012-1

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  11 in total

Review 1.  Theoretical analysis of mutation hotspots and their DNA sequence context specificity.

Authors:  Igor B Rogozin; Youri I Pavlov
Journal:  Mutat Res       Date:  2003-09       Impact factor: 2.433

2.  Optimizing the success of random searches.

Authors:  G M Viswanathan; S V Buldyrev; S Havlin; M G da Luz; E P Raposo; H E Stanley
Journal:  Nature       Date:  1999-10-28       Impact factor: 49.962

Review 3.  Is evolvability evolvable?

Authors:  Massimo Pigliucci
Journal:  Nat Rev Genet       Date:  2008-01       Impact factor: 53.242

4.  Long-term dynamics of adaptation in asexual populations.

Authors:  Michael J Wiser; Noah Ribeck; Richard E Lenski
Journal:  Science       Date:  2013-11-14       Impact factor: 47.728

5.  Optimal foraging strategies: Lévy walks balance searching and patch exploitation under a very broad range of conditions.

Authors:  Nicolas E Humphries; David W Sims
Journal:  J Theor Biol       Date:  2014-06-02       Impact factor: 2.691

6.  Mutation rates in mammalian genomes.

Authors:  Sudhir Kumar; Sankar Subramanian
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-15       Impact factor: 11.205

7.  Conserved noncoding elements follow power-law-like distributions in several genomes as a result of genome dynamics.

Authors:  Dimitris Polychronopoulos; Diamantis Sellis; Yannis Almirantis
Journal:  PLoS One       Date:  2014-05-02       Impact factor: 3.240

8.  Tempo and mode of genome evolution in a 50,000-generation experiment.

Authors:  Olivier Tenaillon; Jeffrey E Barrick; Noah Ribeck; Daniel E Deatherage; Jeffrey L Blanchard; Aurko Dasgupta; Gabriel C Wu; Sébastien Wielgoss; Stéphane Cruveiller; Claudine Médigue; Dominique Schneider; Richard E Lenski
Journal:  Nature       Date:  2016-08-01       Impact factor: 49.962

9.  Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations.

Authors:  Yun Rose Li; Joseph T Glessner; Bradley P Coe; Jin Li; Maede Mohebnasab; Xiao Chang; John Connolly; Charlly Kao; Zhi Wei; Jonathan Bradfield; Cecilia Kim; Cuiping Hou; Munir Khan; Frank Mentch; Haijun Qiu; Marina Bakay; Christopher Cardinale; Maria Lemma; Debra Abrams; Andrew Bridglall-Jhingoor; Meckenzie Behr; Shanell Harrison; George Otieno; Alexandria Thomas; Fengxiang Wang; Rosetta Chiavacci; Lawrence Wu; Dexter Hadley; Elizabeth Goldmuntz; Josephine Elia; John Maris; Robert Grundmeier; Marcella Devoto; Brendan Keating; Michael March; Renata Pellagrino; Struan F A Grant; Patrick M A Sleiman; Mingyao Li; Evan E Eichler; Hakon Hakonarson
Journal:  Nat Commun       Date:  2020-01-14       Impact factor: 14.919

10.  Large chromosomal rearrangements during a long-term evolution experiment with Escherichia coli.

Authors:  Colin Raeside; Joël Gaffé; Daniel E Deatherage; Olivier Tenaillon; Adam M Briska; Ryan N Ptashkin; Stéphane Cruveiller; Claudine Médigue; Richard E Lenski; Jeffrey E Barrick; Dominique Schneider
Journal:  mBio       Date:  2014-09-09       Impact factor: 7.867

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  1 in total

1.  A one-dimensional parameter-free model for carcinogenesis in gene expression space.

Authors:  Roberto Herrero; Dario A Leon; Augusto Gonzalez
Journal:  Sci Rep       Date:  2022-03-19       Impact factor: 4.379

  1 in total

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