Tarek Zaidieh1,2, James R Smith3, Karen E Ball3, Qian An4. 1. School of Pharmacy and Biomedical Sciences, Institute of Biological and Biomedical Sciences, University of Portsmouth, St Michael's Building, White Swan Road, Portsmouth, PO1 2DT, UK. tarek.zaidieh@port.ac.uk. 2. Institute of Life Science, Swansea University Medical School, Swansea, SA2 8PP, UK. tarek.zaidieh@port.ac.uk. 3. School of Pharmacy and Biomedical Sciences, Institute of Biological and Biomedical Sciences, University of Portsmouth, St Michael's Building, White Swan Road, Portsmouth, PO1 2DT, UK. 4. School of Pharmacy and Biomedical Sciences, Institute of Biological and Biomedical Sciences, University of Portsmouth, St Michael's Building, White Swan Road, Portsmouth, PO1 2DT, UK. qian.an@port.ac.uk.