Literature DB >> 33968277

False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma.

Ahmed Abdulrahman Alruwaili1,2,3, Alaa Khalid Alduraibi4, Mohammed Fahed Alzayed1,2,3.   

Abstract

A healthy 52-year-old man started to have few minutes spells of palpitation, tachycardia, hot flashes, and chest tightness. He had a lab work-up for carcinoid, including 5-hydroxyindoleacetic acid (5-HIAA), which was negative. Months later, his symptoms became worse which warranted further investigation to exclude carcinoid disease. Gallium-68 DOTATATE positron emission tomography combined with computed tomography (PET/CT) scanning was performed to assess the patient for carcinoid tumor. It showed foci of radiotracer avidity in the thoracic and lumber spine. Magnetic resonance imaging (MRI) for the vertebral lesions showed atypical hemangioma. Subsequently, follow-up serum chromogranin A testing was negative. © Korean Society of Nuclear Medicine 2021.

Entities:  

Keywords:  68-Gallium DOTATATE; Magnetic resonance imaging; Somatostatin receptors; Vertebral hemangioma

Year:  2021        PMID: 33968277      PMCID: PMC8053631          DOI: 10.1007/s13139-021-00682-x

Source DB:  PubMed          Journal:  Nucl Med Mol Imaging        ISSN: 1869-3474


  11 in total

1.  Prognostic factors and survival in endocrine tumor patients: comparison between gastrointestinal and pancreatic localization.

Authors:  Francesco Panzuto; Silvia Nasoni; Massimo Falconi; Vito Domenico Corleto; Gabriele Capurso; Sara Cassetta; Michela Di Fonzo; Valentina Tornatore; Massimo Milione; Stefano Angeletti; Maria Sofia Cattaruzza; Vincenzo Ziparo; Cesare Bordi; Paolo Pederzoli; Gianfranco Delle Fave
Journal:  Endocr Relat Cancer       Date:  2005-12       Impact factor: 5.678

2.  The Impact of 68Ga-DOTATATE PET/CT Imaging on Management of Patients with Neuroendocrine Tumors: Experience from a National Referral Center in the United Kingdom.

Authors:  Evangelia Skoura; Sofia Michopoulou; Mullan Mohmaduvesh; Emmanouil Panagiotidis; Mohammed Al Harbi; Christos Toumpanakis; Omar Almukhailed; Irfan Kayani; Rizwan Syed; Shaunak Navalkissoor; Peter J Ell; Martyn E Caplin; Jamshed Bomanji
Journal:  J Nucl Med       Date:  2015-10-15       Impact factor: 10.057

3.  Adolescent With 68Ga DOTATATE-Avid Vertebral Hemangioma Mimicking Metastasis in PET Imaging.

Authors:  Evangelia Skoura; Alshaima Alshammari; Rizwan Syed; Rakesh Sajjan; Jamshed Bomanji
Journal:  Clin Nucl Med       Date:  2015-07       Impact factor: 7.794

4.  68Ga-DOTA-TOC uptake in neuroendocrine tumour and healthy tissue: differentiation of physiological uptake and pathological processes in PET/CT.

Authors:  A Kroiss; D Putzer; C Decristoforo; C Uprimny; B Warwitz; B Nilica; M Gabriel; D Kendler; D Waitz; G Widmann; I J Virgolini
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-01-05       Impact factor: 9.236

5.  Vertebral metastases from neuroendocrine tumours: How to avoid false positives on 68Ga-DOTA-TOC PET using CT pattern analysis?

Authors:  Mathieu Gauthé; Nathalie Testart Dardel; Fernando Ruiz Santiago; Jessica Ohnona; Valérie Nataf; Françoise Montravers; Jean-Noël Talbot
Journal:  Eur Radiol       Date:  2018-03-12       Impact factor: 5.315

6.  Localisation of endocrine-related tumours with radioiodinated analogue of somatostatin.

Authors:  E P Krenning; W H Bakker; W A Breeman; J W Koper; P P Kooij; L Ausema; J S Lameris; J C Reubi; S W Lamberts
Journal:  Lancet       Date:  1989-02-04       Impact factor: 79.321

7.  Biodistribution of the Ga-68 labeled somatostatin analogue DOTA-NOC in patients with neuroendocrine tumors: characterization of uptake in normal organs and tumor lesions.

Authors:  V Prasad; R P Baum
Journal:  Q J Nucl Med Mol Imaging       Date:  2010-02       Impact factor: 2.346

8.  Clinical value of ⁶⁸Ga-DOTATATE-PET/CT compared to stand-alone contrast enhanced CT for the detection of extra-hepatic metastases in patients with neuroendocrine tumours (NET).

Authors:  D R Albanus; J Apitzsch; Z Erdem; O Erdem; F A Verburg; F F Behrendt; F M Mottaghy; A Heinzel
Journal:  Eur J Radiol       Date:  2015-06-29       Impact factor: 3.528

9.  Somatostatin analogue scintigraphy in granulomatous diseases.

Authors:  P M Vanhagen; E P Krenning; J C Reubi; D J Kwekkeboom; W H Bakker; A H Mulder; I Laissue; H C Hoogstede; S W Lamberts
Journal:  Eur J Nucl Med       Date:  1994-06

10.  The carcinoid syndrome: comparison of 21 necropsy subjects with carcinoid heart disease to 15 necropsy subjects without carcinoid heart disease.

Authors:  E M Ross; W C Roberts
Journal:  Am J Med       Date:  1985-09       Impact factor: 4.965

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