| Literature DB >> 33968211 |
Miloš Todorović1, Shuliang Jiao2, George Stoica3, Lihong V Wang1.
Abstract
We report on the use of a fiber-based Mueller-matrix optical coherence tomography (OCT) system with continuous source-polarization modulation for in vivo imaging of early stages of skin cancer in SENCAR mice. A homemade hand-held probe with integrated optical scanning and beam delivering optics was coupled in the sample arm. The OCT images show the morphological changes in skin resulting from pre-cancerous papilloma formations that are consistent with histology, thus demonstrating the system's potential for early skin cancer detection.Entities:
Keywords: Coherence imaging; birefringence; medical and biological imaging; optical coherence tomography; polarization; turbid media
Year: 2009 PMID: 33968211 PMCID: PMC8101947 DOI: 10.1142/s1793545809000577
Source DB: PubMed Journal: J Innov Opt Health Sci