[Cholinergic mechanism of neostriatal regulation of conditioned readjustment of posture in dogs].

In chronic experiments on 4 dogs with instrumental reflex of avoidance associated with the maintenance of flexor posture, the effect of application of carbocholine to the nucleus caudatus on realization of components of conditioned readjustment of the posture, was studied. Administration of 1 mkg of carbocholine into the neostriatum led to a general depression of the behaviour whereas 0.1 mkg exerted no effect. Contralateral administration of the same dose into the neostriatum altered the main component of the posture readjustment.