Literature DB >> 33967022

Pain, symptom distress, and pain barriers by age among patients with cancer receiving hospice care: Comparison of baseline data.

Saunjoo L Yoon1, Lisa Scarton2, Laurie Duckworth3, Yingwei Yao4, Miriam O Ezenwa5, Marie L Suarez6, Robert E Molokie7, Diana J Wilkie8.   

Abstract

OBJECTIVES: Age group differences have been reported for pain and symptom presentations in outpatient and inpatient oncology settings, but it is unknown if these differences occur in hospice. We examined whether there were differences in pain, symptom distress, pain barriers, and comorbidities among three age groups (20-64 years, 65-84 years, and 85+) of hospice patients with cancer.
MATERIALS AND METHODS: Participants were recruited from two hospices. Half were women; 49% White and 34% Black. 42% were 20-64 y, 43% 65-84 y, and 15% 85+ y. We analyzed baseline data for 230 hospice patients with cancer (enrolled 2014-2016, mean age 68.2 ± 14.0, 20-100 years) from a stepped-wedge randomized controlled trial. Measures were the Average pain intensity (API, 0-10: current, least and worst pain intensity during the past 24 h), Symptom Distress Scale (SDS, 13-65), Barriers Questionnaire-13 (BQ-13, 0-5), and comorbid conditions. Descriptive, bivariate association, and multiple regression analyses were performed.
RESULTS: Mean API scores differed (p < .001) among the three age groups (5.6 ± 2.0 [20-64 years], 4.7 ± 2.0 [65-84 years], and 4.4 ± 1.8 [85+], as did the mean SDS scores (36.1 ± 7.3, 33.5 ± 8.1, and 31.6 ± 6.6, p = .004). BQ-13 mean scores (2.6 ± 0.9, 2.7 ± 0.8, and 2.5 ± 0.7) and comorbidities were not significantly different across age groups. In multiple regression analyses, age-related differences in API and SDS remained significant after adjusting for gender, race, cancer, palliative performance score, and comorbidities. Comorbidities were positively associated with SDS (p = .046) but not with API (p = .64) in the regression model.
CONCLUSION: Older hospice patients with cancer reported less pain and symptoms than younger patients, but all groups reported similar barriers to pain management. These findings suggest the need for age- and race-sensitive interventions to reduce pain and symptom distress levels at life's end.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Age difference; Cancer; Hospice; Oldest-old; Pain; Palliative care; Race and ethnicity; Survival; Symptom distress

Mesh:

Year:  2021        PMID: 33967022      PMCID: PMC8429256          DOI: 10.1016/j.jgo.2021.04.008

Source DB:  PubMed          Journal:  J Geriatr Oncol        ISSN: 1879-4068            Impact factor:   3.929


  58 in total

Review 1.  Cancer-Incidence, prevalence and mortality in the oldest-old. A comprehensive review.

Authors:  Shantell C Nolen; Marcella A Evans; Avital Fischer; Maria M Corrada; Claudia H Kawas; Daniela A Bota
Journal:  Mech Ageing Dev       Date:  2017-05-11       Impact factor: 5.432

2.  The measurement of clinical pain intensity: a comparison of six methods.

Authors:  Mark P Jensen; Paul Karoly; Sanford Braver
Journal:  Pain       Date:  1986-10       Impact factor: 6.961

3.  Symptom frequency and change of oldest old cancer patients.

Authors:  Linda Pang; Maxine de la Cruz; Jimin Wu; Diane Liu; Mujtaba Naqvi; Eduardo Bruera
Journal:  Support Care Cancer       Date:  2019-02-23       Impact factor: 3.603

4.  Prevalence and relevance of pain in older persons.

Authors:  Stephen J Gibson; David Lussier
Journal:  Pain Med       Date:  2012-04       Impact factor: 3.750

5.  Patient-related barriers to management of cancer pain.

Authors:  Sandra E Ward; Nancy Goldberg; Vickie Miller-McCauley; Carol Mueller; Ann Nolan; Darlene Pawlik-Plank; Alice Robbins; Doris Stormoen; David E Weissman
Journal:  Pain       Date:  1993-03       Impact factor: 6.961

Review 6.  When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly.

Authors:  Klaus Turnheim
Journal:  Exp Gerontol       Date:  2003-08       Impact factor: 4.032

7.  A Stepped-Wedge Randomized Controlled Trial: Effects of eHealth Interventions for Pain Control Among Adults With Cancer in Hospice.

Authors:  Diana J Wilkie; Yingwei Yao; Miriam O Ezenwa; Marie L Suarez; Brenda W Dyal; Anayza Gill; Theresa Hipp; Robert Shea; Jacob Miller; Karen Frank; Nargis Nardi; Michael Murray; Julie Glendenning; Jessica Perez; Jesus D Carrasco; David Shuey; Veronica Angulo; Timothy McCurry; Joanna Martin; Adrienne Butler; Zaijie Jim Wang; Robert E Molokie
Journal:  J Pain Symptom Manage       Date:  2019-11-09       Impact factor: 3.612

8.  Symptom clusters in patients with cancer in the hospice/palliative care setting.

Authors:  Stephen J Stapleton; Janean Holden; Joel Epstein; Diana J Wilkie
Journal:  Support Care Cancer       Date:  2016-04-15       Impact factor: 3.603

9.  Barriers to pain management in a community sample of Chinese American patients with cancer.

Authors:  Janet Edrington; Angela Sun; Candice Wong; Marylin Dodd; Geraldine Padilla; Steven Paul; Christine Miaskowski
Journal:  J Pain Symptom Manage       Date:  2008-11-12       Impact factor: 3.612

Review 10.  Could epigenetics help explain racial disparities in chronic pain?

Authors:  Edwin N Aroke; Paule V Joseph; Abhrarup Roy; Demario S Overstreet; Trygve O Tollefsbol; David E Vance; Burel R Goodin
Journal:  J Pain Res       Date:  2019-02-18       Impact factor: 3.133

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