César Álvarez-Marcos1,2,3,4, Andrea Vicente Benito5, Agueda Gayol Fernández5, Daniel Pedregal-Mallo1,2,3, Paloma Sirgo Rodríguez5, Liliana Santamarina Rabanal5, José Luis Llorente1,2,3,4, Fernando López6,7,8,9, Juan Pablo Rodrigo1,2,3,4. 1. Department of Otolaryngology, Hospital Universitario Central de Asturias (HUCA), Avenida de Roma, s/n, 33011, Oviedo, Spain. 2. Department of Head and Neck Cancer, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain. 3. Instituto Universitario de Oncología del Principado de Asturias (IUOPA), University of Oviedo, Oviedo, Spain. 4. CIBERONC, Instituto de Salud Carlos III, Madrid, Spain. 5. Speech Therapy, Faculty of Psychology, University of Oviedo, Oviedo, Spain. 6. Department of Otolaryngology, Hospital Universitario Central de Asturias (HUCA), Avenida de Roma, s/n, 33011, Oviedo, Spain. flopez_1981@yahoo.es. 7. Department of Head and Neck Cancer, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain. flopez_1981@yahoo.es. 8. Instituto Universitario de Oncología del Principado de Asturias (IUOPA), University of Oviedo, Oviedo, Spain. flopez_1981@yahoo.es. 9. CIBERONC, Instituto de Salud Carlos III, Madrid, Spain. flopez_1981@yahoo.es.
Abstract
PURPOSE: Patients with advanced laryngeal and hypopharyngeal cancer are often treated with chemo-radiotherapy to avoid total laryngectomy. Subclinical swallowing disorders could be present in these patients even though patients do not complain of any symptoms. We sought to evaluate the impact of chemoradiation on swallowing and quality of life. METHODS: We studied 21 patients undergoing chemo-radiotherapy for advanced laryngeal and hypopharyngeal cancer. All patients were tumor-free and none reported symptoms related to dysphagia during follow-up or showed altered routine screening tests (EAT-10) to detect it. Swallowing functions were assessed using volume-viscosity swallow test (V-VST) and fiberoptic endoscopic evaluation of swallowing (FEES). Quality of life was assessed with the EORT-H&N35, and SWAL-QOL scales. RESULTS: Frequent alterations in swallowing efficacy (100%) and safety (85.5%) were detected with V-VST and FEES. Quality-of-life scales showed a reduction in their scores between 12 and 17%, mainly in the areas of symptoms. CONCLUSION: Swallowing disorders are common after chemo-radiotherapy, even in patients who do not clinically manifest these disorders, contributing to a decrease in patients' quality of life. FEES and V-VST are useful procedures to detect asymptomatic swallowing disorders.
PURPOSE: Patients with advanced laryngeal and hypopharyngeal cancer are often treated with chemo-radiotherapy to avoid total laryngectomy. Subclinical swallowing disorders could be present in these patients even though patients do not complain of any symptoms. We sought to evaluate the impact of chemoradiation on swallowing and quality of life. METHODS: We studied 21 patients undergoing chemo-radiotherapy for advanced laryngeal and hypopharyngeal cancer. All patients were tumor-free and none reported symptoms related to dysphagia during follow-up or showed altered routine screening tests (EAT-10) to detect it. Swallowing functions were assessed using volume-viscosity swallow test (V-VST) and fiberoptic endoscopic evaluation of swallowing (FEES). Quality of life was assessed with the EORT-H&N35, and SWAL-QOL scales. RESULTS: Frequent alterations in swallowing efficacy (100%) and safety (85.5%) were detected with V-VST and FEES. Quality-of-life scales showed a reduction in their scores between 12 and 17%, mainly in the areas of symptoms. CONCLUSION: Swallowing disorders are common after chemo-radiotherapy, even in patients who do not clinically manifest these disorders, contributing to a decrease in patients' quality of life. FEES and V-VST are useful procedures to detect asymptomatic swallowing disorders.
Authors: Lisette van der Molen; Wilma D Heemsbergen; Rianne de Jong; Maya A van Rossum; Ludi E Smeele; Coen R N Rasch; Frans J M Hilgers Journal: Radiother Oncol Date: 2013-03-26 Impact factor: 6.280
Authors: David O Francis; Ernest A Weymuller; Upendra Parvathaneni; Albert L Merati; Bevan Yueh Journal: Ann Otol Rhinol Laryngol Date: 2010-06 Impact factor: 1.547
Authors: S A C Kraaijenga; I M Oskam; L van der Molen; O Hamming-Vrieze; F J M Hilgers; M W M van den Brekel Journal: Oral Oncol Date: 2015-05-28 Impact factor: 5.337
Authors: Irene Jacobi; Lisette van der Molen; Hermelinde Huiskens; Maya A van Rossum; Frans J M Hilgers Journal: Eur Arch Otorhinolaryngol Date: 2010-06-30 Impact factor: 2.503
Authors: César Álvarez-Marcos; Andrea Vicente-Benito; Águeda Gayol-Fernández; Daniel Pedregal-Mallo; Paloma Sirgo-Rodríguez; Liliana Santamarina-Rabanal; José Luis Llorente; Fernando López; Juan Pablo Rodrigo Journal: Acta Otorhinolaryngol Ital Date: 2022-06 Impact factor: 2.618