A protocol for the investigation of infants and children with urinary tract infection.

An investigation protocol, designed to reduce invasive procedures to a minimum, is described for the detection of reflux nephropathy in infants and children. Intravenous urography and voiding cysto-urethrography is necessary in patients up to the age of 2 years presenting with urinary tract infection, but in children over 2 years of age the protocol limits the investigation to an intravenous urogram unless this is abnormal. A review of this policy after 5 years has indicated that it is appropriate provided that children who continue to have infections have further evaluation including a voiding cysto-urethrogram.