Literature DB >> 3396269

A study of HLA class II antigens in an Italian paediatric population with coeliac disease.

M Morellini1, S Trabace, M C Mazzilli, P Lulli, S Cappellacci, M Bonamico, I Margarit, E Gandini.   

Abstract

One hundred and twenty-one Italian children with coeliac disease (CD) have been compared with a control population from the same geographical area for the distribution of HLA-DR and DQ antigens. The pattern of an increase in DR3, DR7, and of heterozygotes DR5/7 was associated with an excess of heterozygotes DQw2/DQw3 in the CD population. These findings suggest that epitopes determined by specific combinations of DQ alpha and beta chains (combinatorial determinants) predispose to the disease.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3396269

Source DB:  PubMed          Journal:  Dis Markers        ISSN： 0278-0240            Impact factor:   3.434


  8 in total

Review 1.  The immunology of coeliac disease.

Authors:  G J Mantzaris; W M Rosenberg; D P Jewell
Journal:  Springer Semin Immunopathol       Date:  1990

Review 2.  Understanding the molecular basis of coeliac disease.

Authors:  M F Kagnoff
Journal:  Gut       Date:  1990-05       Impact factor: 23.059

3.  Molecular analysis of HLA-DQ A alleles in coeliac disease lack of a unique disease-associated sequence.

Authors:  V Mantovani; G R Corazza; G Angelini; L Delfino; M Frisoni; P Mirri; R A Valentini; P Barboni; G Gasbarrini; G B Ferrara
Journal:  Clin Exp Immunol       Date:  1991-01       Impact factor: 4.330

4.  A locus telomeric to HLA-DPB encodes susceptibility to coeliac disease.

Authors:  W M Rosenberg; B P Wordsworth; D P Jewell; J I Bell
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

5.  Structural analysis of the HLA-DR, -DQ, and -DP alleles on the celiac disease-associated HLA-DR3 (DRw17) haplotype.

Authors:  M F Kagnoff; J I Harwood; T L Bugawan; H A Erlich
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

6.  Genetic difference in HLA-DR phenotypes between coeliac disease and transitory gluten intolerance.

Authors:  R Meuli; W J Pichler; H Gaze; M J Lentze
Journal:  Arch Dis Child       Date:  1995-01       Impact factor: 3.791

7.  TAP1 and TAP2 polymorphism in coeliac disease.

Authors:  S H Powis; W M Rosenberg; M Hall; I Mockridge; S Tonks; A Ivinson; P J Ciclitira; D P Jewell; J S Lanchbury; J I Bell
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846

8.  Human leucocyte class I and II antigens in coeliac disease: a study in an Austrian paediatric population.

Authors:  B M Winklhofer-Roob; E Rossipal; G Lanzer
Journal:  Eur J Pediatr       Date:  1991-08       Impact factor: 3.183
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.