Literature DB >> 33962193

Formononetin: Biological effects and uses - A review.

Juliana Machado Dutra1, Paula J P Espitia2, Rejane Andrade Batista3.   

Abstract

Formononetin (FORM) is an isoflavone from the group of phytoestrogens that exhibits a broad spectrum of physiological effects beneficial to health through dependent and independent mechanisms of estrogen. This article aimed to present FORM main functions and future prospects for applications in different areas. Scientific publications and patents dated between 1998 and 2019 were analyzed. FORM has potential as an active compound of interest to product development for the industries of food, medicine, and cosmetics, among others. Moreover, in the medical area, this active compound has shown potential in the prevention and treatment of several diseases, including chronic ones, such as cancer, obesity, and neurodegenerative diseases.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Biological effects; Formononetin; Isoflavone

Year:  2021        PMID： 33962193     DOI： 10.1016/j.foodchem.2021.129975

Source DB:  PubMed          Journal:  Food Chem        ISSN： 0308-8146            Impact factor:   7.514


  9 in total

1.  Combined LC-MS/MS and Molecular Networking Approach Reveals Antioxidant and Antimicrobial Compounds from Erismadelphus exsul Bark.

Authors:  Morel Essono Mintsa; Elvis Otogo N'nang; Élodie Choque; Ali Siah; Justine Jacquin; Jerome Muchembled; Roland Molinié; Romain Roulard; Dominique Cailleu; Mehdi A Beniddir; Cédric Sima Obiang; Joseph-Privat Ondo; Brice Kumulungui; François Mesnard
Journal:  Plants (Basel)       Date:  2022-06-03

2.  Formononetin Improves the Survival of Random Skin Flaps Through PI3K/Akt-Mediated Nrf2 Antioxidant Defense System.

Authors:  Haoliang Li; Renhao Jiang; Lejing Lou; Chao Jia; Linfang Zou; Mochuan Chen
Journal:  Front Pharmacol       Date:  2022-05-19       Impact factor: 5.988

3.  Formononetin Ameliorates Renal Dysfunction, Oxidative Stress, Inflammation, and Apoptosis and Upregulates Nrf2/HO-1 Signaling in a Rat Model of Gentamicin-Induced Nephrotoxicity.

Authors:  Osama Y Althunibat; Mohammad H Abukhalil; Saleem H Aladaileh; Haitham Qaralleh; Wesam Al-Amarat; Manal A Alfwuaires; Abdulmohsen I Algefare; Nader Ibrahim Namazi; Sahar J Melebary; Ahmad O Babalghith; Carlos Adam Conte-Junior
Journal:  Front Pharmacol       Date:  2022-05-26       Impact factor: 5.988

4.  A Novel Formononetin Derivative Promotes Anti-ischemic Effects on Acute Ischemic Injury in Mice.

Authors:  Lin Zhao; Jing Han; Jiaqi Liu; Kechen Fan; Tianjie Yuan; Ju Han; Liangliang Chen; Sen Zhang; Ming Zhao; Jinao Duan
Journal:  Front Microbiol       Date:  2021-12-14       Impact factor: 5.640

5.  Mechanism of Xinfeng Capsule in the Treatment of Hypercoagulable State of Ankylosing Spondylitis Based on Data Mining and Network Pharmacology.

Authors:  Xu Li; Jian Liu; Yanyan Fang; Mingyu He; Fanfan Wang; Qi Han
Journal:  Biomed Res Int       Date:  2022-03-17       Impact factor: 3.411

Review 6.  Formononetin: A Pathway to Protect Neurons.

Authors:  Xiaoyu Ma; Juejin Wang
Journal:  Front Integr Neurosci       Date:  2022-07-13

7.  Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.

Authors:  Lu Shi; Yiying Zhao; Chenran Feng; Feng Miao; Linlin Dong; Tianquan Wang; Antony Stalin; Jingyuan Zhang; Jingru Tu; Kexin Liu; Wenyan Sun; Jiarui Wu
Journal:  Front Pharmacol       Date:  2022-08-17       Impact factor: 5.988

Review 8.  Thioredoxin-interacting protein (TXNIP) as a target for Alzheimer's disease: flavonoids and phenols.

Authors:  Meng Zhang; Guanhua Hu; Nan Shao; Yunpeng Qin; Qian Chen; Yan Wang; Peng Zhou; Biao Cai
Journal:  Inflammopharmacology       Date:  2021-08-04       Impact factor: 4.473

9.  Formononetin protects against ox-LDL-induced endothelial dysfunction by activating PPAR-γ signaling based on network pharmacology and experimental validation.

Authors:  Baohua Zhang; Zhongwei Hao; Wenli Zhou; Shan Zhang; Mingyan Sun; Honglei Li; Naijing Hou; Cui Jing; Mingxing Zhao
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269
  9 in total

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