Literature DB >> 33960295

Acute lacunar infarct in an obese adolescent with obstructive sleep apnea.

Brian Chen1, Sasikanth Gorantla2, Vaishal Shah3.   

Abstract

Obstructive sleep apnea is associated with an increased risk of acute ischemic cerebrovascular accidents in adults. However, this association has not been well established in the pediatric population. We report a case of acute right internal capsule lacunar infarct manifesting as left-sided hemiplegia in an adolescent with severe obesity. Severe untreated obstructive sleep apnea was identified during the hospital stay. Positive airway pressure therapy, weight loss, and tonsillectomy eventually normalized sleep-disordered breathing. The patient recovered completely without any residual neurological deficits with multidisciplinary care. Lacunar infarcts due to hypertension-related cerebral vasculopathy are a well-known cause of stroke in adults. Untreated obstructive sleep apnea may cause hypertension and potentially predispose even the pediatric population to develop lacunar infarcts. Polysomnography needs to be considered as a part of the diagnostic algorithm in pediatric patients with stroke. CITATION: Chen B, Gorantla S, Shah V. Acute lacunar infarct in an obese adolescent with obstructive sleep apnea. J Clin Sleep Med. 2021;17(8):1743-1747.
© 2021 American Academy of Sleep Medicine.

Entities:  

Keywords:  ischemic stroke; obstructive sleep apnea; pediatric obesity

Mesh:

Year:  2021        PMID: 33960295      PMCID: PMC8656918          DOI: 10.5664/jcsm.9390

Source DB:  PubMed          Journal:  J Clin Sleep Med        ISSN: 1550-9389            Impact factor:   4.324


  12 in total

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Review 2.  Excess body weight and incidence of stroke: meta-analysis of prospective studies with 2 million participants.

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Review 4.  Using the National Institutes of Health Stroke Scale: A Cautionary Tale.

Authors:  Patrick Lyden
Journal:  Stroke       Date:  2017-01-11       Impact factor: 7.914

5.  Infarct location and sleep apnea: evaluating the potential association in acute ischemic stroke.

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Journal:  Sleep Med       Date:  2015-07-17       Impact factor: 3.492

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Authors:  Ida Gillberg Andersen; Jens-Christian Holm; Preben Homøe
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2016-06-06       Impact factor: 1.675

7.  Continuous positive airway pressure treatment reduces mortality in patients with ischemic stroke and obstructive sleep apnea: a 5-year follow-up study.

Authors:  Miguel Angel Martínez-García; Juan José Soler-Cataluña; Laura Ejarque-Martínez; Youssef Soriano; Pilar Román-Sánchez; Ferrán Barbé Illa; Josep María Montserrat Canal; Joaquín Durán-Cantolla
Journal:  Am J Respir Crit Care Med       Date:  2009-04-30       Impact factor: 21.405

8.  Prevalence of obesity and severe obesity in US children, 1999-2014.

Authors:  Asheley Cockrell Skinner; Eliana M Perrin; Joseph A Skelton
Journal:  Obesity (Silver Spring)       Date:  2016-05       Impact factor: 5.002

Review 9.  Obstructive sleep apnea in children: a critical update.

Authors:  Hui-Leng Tan; David Gozal; Leila Kheirandish-Gozal
Journal:  Nat Sci Sleep       Date:  2013-09-25

10.  Comparison of Risk Factor between Lacunar Stroke and Large Artery Atherosclerosis Stroke: A Cross-Sectional Study in China.

Authors:  Pu Lv; Haiqiang Jin; Yuanyuan Liu; Wei Cui; Qing Peng; Ran Liu; Wei Sun; Chenghe Fan; Yuming Teng; Weiping Sun; Yining Huang
Journal:  PLoS One       Date:  2016-03-02       Impact factor: 3.240

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