Literature DB >> 33959790

Rare presentation of intradural calcium pyrophosphate dihydrate crystal deposition.

Daniel P Gewolb1, Pouya Entezami2, John W German3, Ananth Narayan1.   

Abstract

Calcium pyrophosphate dihydrate crystal deposition (CPPD), also known as pseudogout, can have spinal manifestations in roughly one quarter of patients. We present a rare, intradural manifestation of CPPD requiring surgical intervention, with a review of pertinent differential diagnoses on imaging. A 48-year-old male presented with urinary retention, and was found to have an intradural lesion with peripheral enhancement on gadolinium T1-weighted magnetic resonance imaging. Due to the patient's progressive neurological deterioration, he was taken for a minimally invasive approach for resection of the lesion. Histopathological analysis revealed crystal deposits with rhomboidal birefringence consistent with CPPD. The imaging features of this lesion were atypical for any of the traditional intradural extramedullary lesions. Typically seen extradurally, recognizing CPPD as a potential culprit for intradural compression is helpful to recognize for providers.

Entities:  

Keywords:  CPPD; Calcium pyrophosphate dihydrate crystal deposition; Intradural; Pseudogout; Spine

Year:  2021        PMID: 33959790     DOI: 10.1007/s00234-021-02726-7

Source DB:  PubMed          Journal:  Neuroradiology        ISSN: 0028-3940            Impact factor:   2.804


  1 in total

Review 1.  Imaging of chondrocalcinosis: calcium pyrophosphate dihydrate (CPPD) crystal deposition disease -- imaging of common sites of involvement.

Authors:  N Magarelli; R Amelia; N Melillo; M Nasuto; F Cantatore; G Guglielmi
Journal:  Clin Exp Rheumatol       Date:  2012-03-07       Impact factor: 4.473

  1 in total
  1 in total

1.  Pseudogout, an unconventional imitator of the lumbosacral spine with associated chronic epidural hematoma: illustrative cases.

Authors:  Stephen Jaffee; Seung Won Jeong; Rocco Dabecco; Shahed Elhamdani; Alexander Yu
Journal:  J Neurosurg Case Lessons       Date:  2022-02-21
  1 in total

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