Literature DB >> 33959785

Outcomes of post-chemotherapy robot-assisted retroperitoneal lymph node dissection in testicular cancer: multi-institutional study.

Haidar Abdul-Muhsin1, Nicholas Rocco2, Anojan Navaratnam3, Michael Woods4, James L'Esperance2, Erik Castle5, Sean Stroup2.   

Abstract

OBJECTIVE: To evaluate the perioperative and oncological outcomes after post-chemotherapy robot-assisted retroperitoneal lymph node dissection (PC-RARPLND).
MATERIALS AND METHODS: We retrospectively reported the perioperative and oncological outcomes of all the patients with testicular cancer who underwent PC-RARPLND at three tertiary teaching centers. Descriptive statistical measures were used to report demographic, clinical, intraoperative, postoperative and oncological outcomes.
RESULTS: There were 43 consecutive patients who underwent PC-RARPLND at the participating institutions. Mean patient age was 29.2 years (± 8.2), BMI was 26.6 kg/m2 (± 6.2). The mean size of retroperitoneal mass was 4.1 cm (± 3.5). Full bilateral template dissection was performed in 38 (88.3%) patients. Nerve sparing was attempted in 19 (44.1%) patients. Mean operative time was 374 min (± 132) and estimated blood loss was 292 ml (± 445.6). The mean postoperative LOS was 2.8 days (± 5.9). There was a total of 12 complications in 10 patients (Clavien grade I = 5, II = 3, III = 3 and IV = 1). Postoperative pathology demonstrated 24 patients (55%) with necrosis/fibrosis, 16 (37%) with teratoma and 3 (7%) with viable tumor. Mean lymph node (LN) yield was 26.5 LNs (SD ± 16.1). Patients were followed for a mean of 30.7 months (± 24.7). No deaths were documented during follow-up and 2 pulmonary recurrences were identified. Antegrade ejaculation was preserved in 70.6% of patient who underwent nerve sparing. Limitations included retrospective nature and limited follow up.
CONCLUSION: PC-RAPLND is safe and technically reproducible. It provides improved morbidity and less convalescence.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Retroperitoneal lymph node dissection; Robotic retroperitoneal lymph node dissection; Testis cancer

Mesh:

Year:  2021        PMID: 33959785     DOI: 10.1007/s00345-021-03712-7

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  3 in total

1.  Risk for Clostridium difficile infection after radical cystectomy for bladder cancer: Analysis of a contemporary series.

Authors:  Nick W Liu; Kashyap Shatagopam; M Francesca Monn; Hristos Z Kaimakliotis; Clint Cary; Ronald S Boris; Matthew J Mellon; Timothy A Masterson; Richard S Foster; Thomas A Gardner; Richard Bihrle; Michael G House; Michael O Koch
Journal:  Urol Oncol       Date:  2015-08-14       Impact factor: 3.498

2.  Infiltrative Renal Masses: Clinical Significance and Fidelity of Documentation.

Authors:  Hajime Tanaka; Xiaobo Ding; Yunlin Ye; Yanbo Wang; Rebecca A Campbell; Molly E DeWitt-Foy; Chalairat Suk-Ouichai; Ryan D Ward; Erick M Remer; Jianbo Li; Steven C Campbell
Journal:  Eur Urol Oncol       Date:  2019-08-20

Review 3.  Integration of surgery and systemic therapy: results and principles of integration.

Authors:  J P Donohue; I Leviovitch; R S Foster; J Baniel; P Tognoni
Journal:  Semin Urol Oncol       Date:  1998-05
  3 in total

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