| Literature DB >> 33957537 |
Xiao-Tong Zhao1, Chun Lei1, Jin-Qiu You1, Ting Zhao1, Mei-Hua Yu1, Xun-Long Shi1, Xiao Hu2, Ai-Jun Hou3.
Abstract
Three unprecedented dimeric clerodane diterpenoids, dodovisdimers A-C (1-3), along with six known clerodane monomers (4-9), were isolated from Dodonaea viscosa. Compounds 1-3 may be biosynthetically formed via an intermolecular Diels-Alder [4+2] cycloaddition between the coexisting monomers 4-7. The structures of these clerodanes were characterized by spectroscopic techniques, X-ray crystallographic study, and ECD calculations. Some isolates exerted antiviral effects on human influenza A virus (H3N2) in vitro.Entities:
Keywords: Antiviral activity; Clerodane diterpenoids; Dodonaea viscosa
Year: 2021 PMID： 33957537 DOI： 10.1016/j.bioorg.2021.104916
Source DB: PubMed Journal: Bioorg Chem ISSN： 0045-2068 Impact factor: 5.275