G Bahat1, B Ilhan, A Tufan, H Dogan, M A Karan. 1. Gulistan Bahat, Istanbul University, Istanbul Medical School, Department of Internal Medicine, Capa, 34390, Istanbul, Turkey, Telephone: + 90 212 414 20 00-33204, Fax: + 90 212 532 42 08, E-mail address: gbahatozturk@yahoo.com.
Abstract
OBJECTIVE: Fried frailty scale is the very first and most commonly used assessment scale for an operational definition of frailty with its demonstrated success as a predictor of mobility limitations and mortality. However, it is impractical for use in routine clinical practice. We aimed to study whether a simpler modified Fried frailty scale could predict mortality among nursing home residents. DESIGN: Retrospective longitudinal follow-up study. SETTING: Nursing home. Baseline evaluation was performed in 2009. Mortality was assessed after 4 year. PARTICIPANTS: Two hundred-twenty-four participants were included. MEASUREMENTS: Residents were assessed for demographic characteristics, falls, dementia, the number of regular medications and chronic diseases, body composition by bioimpedance analysis, basic and instrumental activities of daily living besides frailty status by a modified Fried frailty scale. The residents were assessed for mortality after a median follow-up time of 46 months. The association of frailty with mortality was analyzed by the Kaplan-Meier Log-rank test and multivariate Cox Regression analysis. RESULTS: Mortality occurred in 90 (40.2%) of the residents. In multivariate analysis, frailty was an independent predictor of death (Hazzard ratio= 1.4, 95% confidence interval= 1.03-2.6, p=0.03) when adjusted by age, sex, presence of malnutrition, low muscle mass, number of chronic diseases and regular medications. CONCLUSION: Our results suggest that the simpler modified Fried frailty scale can be used as a screening tool for frailty in everyday practice as a tool to identify risky patients for mortality. Future reports studying its role in predicting other adverse outcomes associated with frailty are needed.
OBJECTIVE: Fried frailty scale is the very first and most commonly used assessment scale for an operational definition of frailty with its demonstrated success as a predictor of mobility limitations and mortality. However, it is impractical for use in routine clinical practice. We aimed to study whether a simpler modified Fried frailty scale could predict mortality among nursing home residents. DESIGN: Retrospective longitudinal follow-up study. SETTING: Nursing home. Baseline evaluation was performed in 2009. Mortality was assessed after 4 year. PARTICIPANTS: Two hundred-twenty-four participants were included. MEASUREMENTS: Residents were assessed for demographic characteristics, falls, dementia, the number of regular medications and chronic diseases, body composition by bioimpedance analysis, basic and instrumental activities of daily living besides frailty status by a modified Fried frailty scale. The residents were assessed for mortality after a median follow-up time of 46 months. The association of frailty with mortality was analyzed by the Kaplan-Meier Log-rank test and multivariate Cox Regression analysis. RESULTS:Mortality occurred in 90 (40.2%) of the residents. In multivariate analysis, frailty was an independent predictor of death (Hazzard ratio= 1.4, 95% confidence interval= 1.03-2.6, p=0.03) when adjusted by age, sex, presence of malnutrition, low muscle mass, number of chronic diseases and regular medications. CONCLUSION: Our results suggest that the simpler modified Fried frailty scale can be used as a screening tool for frailty in everyday practice as a tool to identify risky patients for mortality. Future reports studying its role in predicting other adverse outcomes associated with frailty are needed.
Authors: Ellen A Struijk; Teresa T Fung; Fernando Rodríguez-Artalejo; Heike A Bischoff-Ferrari; Frank B Hu; Walter C Willett; Esther Lopez-Garcia Journal: J Cachexia Sarcopenia Muscle Date: 2022-03-23 Impact factor: 12.063
Authors: M Cristina Polidori; Mariana Alves; Gulistan Bahat; Anne Sophie Boureau; Serdar Ozkok; Roman Pfister; Alberto Pilotto; Nicola Veronese; Mario Bo Journal: Eur Geriatr Med Date: 2021-11-02 Impact factor: 1.710