OBJECTIVE: To evaluate the usefulness of ultrasound examination in patients with just a serological diagnosis of schistosomiasis but no other evidence of active infection. METHODS: 346 sub-Saharan patients with possible schistosomiasis that presented at a Tropical Medicine Unit between 2008 and 2019 were retrospectively selected. Possible schistosomiasis was considered in those patients with a positive serology for schistosomasis in the absence of direct microbiological isolates, hematuria and/or eosinophilia. Data from ultrasound examinations before and after treatment with praziquantel were collected and categorized following the World Health Organization-Niamey score to standardize the use of ultrasonography for the assessment of schistosomiasis-related morbidity. RESULTS: Ultrasound examinations were abnormal in only ten patients (2.89%). Main findings were focal thickening of the bladder wall (n = 6), ureteral dilatation (n = 3) and grade I hydronephrosis (n = 1). No malignant lesions, hepatic lesions nor hepatobiliary related disorders were found. After treatment, the S. haematobium global score (5 vs 3.4, p = 0.06) and the urinary bladder score (2 vs 1, p = 0.059) showed a trend towards improvement after treatment. In three patients the score after treatment dropped to 0, and in another three it remained the same although with signs of improvement. No worsening of the score was observed in any case. CONCLUSION: For those patients with a diagnosis of schistosomiasis based solely in a positive serology, the ultrasound examination could safely be spared due to the low prevalence of pathological findings and its response to treatment anyway.
OBJECTIVE: To evaluate the usefulness of ultrasound examination in patients with just a serological diagnosis of schistosomiasis but no other evidence of active infection. METHODS: 346 sub-Saharan patients with possible schistosomiasis that presented at a Tropical Medicine Unit between 2008 and 2019 were retrospectively selected. Possible schistosomiasis was considered in those patients with a positive serology for schistosomasis in the absence of direct microbiological isolates, hematuria and/or eosinophilia. Data from ultrasound examinations before and after treatment with praziquantel were collected and categorized following the World Health Organization-Niamey score to standardize the use of ultrasonography for the assessment of schistosomiasis-related morbidity. RESULTS: Ultrasound examinations were abnormal in only ten patients (2.89%). Main findings were focal thickening of the bladder wall (n = 6), ureteral dilatation (n = 3) and grade I hydronephrosis (n = 1). No malignant lesions, hepatic lesions nor hepatobiliary related disorders were found. After treatment, the S. haematobium global score (5 vs 3.4, p = 0.06) and the urinary bladder score (2 vs 1, p = 0.059) showed a trend towards improvement after treatment. In three patients the score after treatment dropped to 0, and in another three it remained the same although with signs of improvement. No worsening of the score was observed in any case. CONCLUSION: For those patients with a diagnosis of schistosomiasis based solely in a positive serology, the ultrasound examination could safely be spared due to the low prevalence of pathological findings and its response to treatment anyway.
Authors: Joaquín Salas-Coronas; José Vázquez-Villegas; Ana B Lozano-Serrano; Manuel J Soriano-Pérez; Isabel Cabeza-Barrera; María Teresa Cabezas-Fernández; Antonio Villarejo-Ordóñez; José Carlos Sánchez-Sánchez; José Ignacio Abad Vivas-Pérez; Salvador Vázquez-Blanc; Matilde Palanca-Giménez; José A Cuenca-Gómez Journal: Travel Med Infect Dis Date: 2019-11-05 Impact factor: 6.211
Authors: Joaquín Salas-Coronas; María Teresa Cabezas-Fernández; Ana Belén Lozano-Serrano; Manuel Jesús Soriano-Pérez; José Vázquez-Villegas; José Ángel Cuenca-Gómez Journal: Am J Trop Med Hyg Date: 2018-01 Impact factor: 2.345
Authors: Joaquín Salas-Coronas; José Vázquez-Villegas; Antonio Villarejo-Ordóñez; José Carlos Sánchez-Sánchez; José Espada-Chavarría; Manuel Jesús Soriano-Pérez; M Isabel Cabeza-Barrera; M Teresa Cabezas-Fernández Journal: Enferm Infecc Microbiol Clin Date: 2012-06-09 Impact factor: 1.731
Authors: Tilman Lingscheid; Florian Kurth; Jan Clerinx; Stefania Marocco; Begoña Trevino; Mirjam Schunk; José Muñoz; Ida E Gjørup; Tomas Jelinek; Michel Develoux; Graham Fry; Thomas Jänisch; Matthias L Schmid; Olivier Bouchaud; Sabino Puente; Lorenzo Zammarchi; Kristine Mørch; Anders Björkman; Heli Siikamäki; Andreas Neumayr; Henrik Nielsen; Urban Hellgren; Malgorzata Paul; Guido Calleri; Pavel Kosina; Bjørn Myrvang; José M Ramos; Gudrun Just-Nübling; Anna Beltrame; José Saraiva da Cunha; Peter Kern; Laurence Rochat; August Stich; Peter Pongratz; Martin P Grobusch; Norbert Suttorp; Martin Witzenrath; Christoph Hatz; Thomas Zoller Journal: Am J Trop Med Hyg Date: 2017-07-19 Impact factor: 2.345
Authors: J Richter; M C Botelho; M C Holtfreter; R Akpata; T El Scheich; A Neumayr; E Brunetti; C Hatz; Y Dong; C F Dietrich Journal: Z Gastroenterol Date: 2016-07-18 Impact factor: 2.000