Literature DB >> 33947126

Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd.

Eva Klouth1, Yury Zablotski2, Lutz S Goehring1.   

Abstract

Equid herpesvirus type 1 (EHV-1) causes several outbreaks of abortion and/or equid herpesvirus-associated myeloencephalopathy (EHM) worldwide each year. EHM is of great concern, as permanent neurological gait anomalies can leave a horse unfit for future use. The study assesses the risk factors associated with the occurrence of EHM. During an unmitigated outbreak, 141 adult horses/ponies of several distinct breeds were evaluated-using multiple Bayesian logistic regression calculating the odds ratios for breed, age, and sex. In total, 33 of the 141 horses showed signs of EHM. Fjord horses and warmblood horses were overrepresented among those developing EHM. The pony breeds, Welsh and Shetland ponies, were underrepresented. In addition, age and sex were not associated with the risk for EHM. The main limitation was that it was a retrospective analysis with some flaws of documentation. It can be concluded that breed was a significant risk factor for developing EHM during this outbreak.

Entities:  

Keywords:  EHV-1; Fjord horse; equine; horses; risk factors; warmblood

Year:  2021        PMID: 33947126     DOI: 10.3390/pathogens10050537

Source DB:  PubMed          Journal:  Pathogens        ISSN: 2076-0817


  12 in total

1.  Ataxia and paresis with equine herpesvirus type 1 infection in a herd of riding school horses.

Authors:  P A Friday; W K Scarratt; F Elvinger; P J Timoney; A Bonda
Journal:  J Vet Intern Med       Date:  2000 Mar-Apr       Impact factor: 3.333

2.  Nervous disturbances in horses in relation to infection with equine rhinopneumonitis virus.

Authors:  V Bitsch; A Dam
Journal:  Acta Vet Scand       Date:  1971       Impact factor: 1.695

3.  Equine herpesvirus type 1 neurological disease and enterocolitis in mature standardbred horses.

Authors:  S Carman; E Nagy; D Caldwell; T A van Dreumel
Journal:  J Vet Diagn Invest       Date:  1993-04       Impact factor: 1.279

4.  Clinical report of a paralytic syndrome affecting stallions, mares and foals on a thoroughbred studfarm.

Authors:  R E Greenwood; A R Simson
Journal:  Equine Vet J       Date:  1980-07       Impact factor: 2.888

5.  Analysis of equid herpesvirus 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus nonneuropathogenic disease outbreaks.

Authors:  J Nugent; I Birch-Machin; K C Smith; J A Mumford; Z Swann; J R Newton; R J Bowden; G P Allen; N Davis-Poynter
Journal:  J Virol       Date:  2006-04       Impact factor: 5.103

6.  Neurological disease associated with EHV-1-infection in a riding school: clinical and virological characteristics.

Authors:  C van Maanen; M M Sloet van Oldruitenborgh-Oosterbaan; E A Damen; A G Derksen
Journal:  Equine Vet J       Date:  2001-03       Impact factor: 2.888

7.  Outbreak of neurologic disease caused by equine herpesvirus-1 at a university equestrian center.

Authors:  Rick W Henninger; Stephen M Reed; William J Saville; George P Allen; Gregory F Hass; Catherine W Kohn; Cheryl Sofaly
Journal:  J Vet Intern Med       Date:  2007 Jan-Feb       Impact factor: 3.333

8.  Risk factors for development of neurologic disease after experimental exposure to equine herpesvirus-1 in horses.

Authors:  George P Allen
Journal:  Am J Vet Res       Date:  2008-12       Impact factor: 1.156

9.  Case-control study of a multistate equine herpesvirus myeloencephalopathy outbreak.

Authors:  J L Traub-Dargatz; A M Pelzel-McCluskey; L H Creekmore; S Geiser-Novotny; T R Kasari; A M Wiedenheft; E J Bush; K E Bjork
Journal:  J Vet Intern Med       Date:  2013-02-07       Impact factor: 3.333

10.  Genetic Diversity of Persian Arabian Horses and Their Relationship to Other Native Iranian Horse Breeds.

Authors:  Raheleh Sadeghi; Mohammad Moradi-Shahrbabak; Seyed Reza Miraei Ashtiani; Florencia Schlamp; Elissa J Cosgrove; Doug F Antczak
Journal:  J Hered       Date:  2019-03-05       Impact factor: 2.645

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  3 in total

1.  Molecular characteristics and pathogenicity of an equid alphaherpesvirus 1 strain isolated in China.

Authors:  Yue Hu; Qinrui Jia; Jianhua Liu; Wencheng Sun; Zilei Bao; Chuanzhong Che; Guiling Wu; Bin Fan; Duoliang Ran
Journal:  Virus Genes       Date:  2022-05-14       Impact factor: 2.332

2.  Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): infection with Equine Herpesvirus-1.

Authors:  Søren Saxmose Nielsen; Julio Alvarez; Dominique Joseph Bicout; Paolo Calistri; Elisabetta Canali; Julian Ashley Drewe; Bruno Garin-Bastuji; José Luis Gonzales Rojas; Christian Gortázar; Mette Herskin; Virginie Michel; Miguel Ángel Miranda Chueca; Helen Clare Roberts; Barbara Padalino; Paolo Pasquali; Hans Spoolder; Karl Ståhl; Antonio Velarde Calvo; Arvo Viltrop; Christoph Winckler; Andrea Carvelli; Romain Paillot; Alessandro Broglia; Lisa Kohnle; Francesca Baldinelli; Yves Van der Stede
Journal:  EFSA J       Date:  2022-01-12

3.  Oral Administration of Valganciclovir Reduces Clinical Signs, Virus Shedding and Cell-Associated Viremia in Ponies Experimentally Infected with the Equid Herpesvirus-1 C2254 Variant.

Authors:  Côme J Thieulent; Gabrielle Sutton; Marie-Pierre Toquet; Samuel Fremaux; Erika Hue; Christine Fortier; Alexis Pléau; Alain Deslis; Stéphane Abrioux; Edouard Guitton; Stéphane Pronost; Romain Paillot
Journal:  Pathogens       Date:  2022-05-04
  3 in total

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