| Literature DB >> 33936598 |
Toshiki Terao1,2, Junichiro Yuda1, Nobuhiko Yamauchi1, Yong-Mei Guo1, Kaoru Shimada3, Masato Sugano4, Genichiro Ishii4, Yosuke Minami1.
Abstract
Gray zone lymphoma (GZL) is a rare type of B-cell lymphoma characterized by features of both diffuse large B-cell lymphoma and classical Hodgkin lymphoma (cHL). The prognosis of GZL is poorer than that of cHL and mediastinal large B-cell lymphoma. However, an optimal treatment strategy for relapsed/refractory (R/R) GZL has not been established in the clinical setting. The current study reported an excellent clinical response in a patient with R/R CD30-positive GZL who received brentuximab vedotin (BV) maintenance after autologous stem cell transplantation (ASCT). Although the patient was resistant to prior treatments, BV maintenance after ASCT achieved long-term remission. Hence, BV was determined to be a safe and effective therapeutic option for CD30-positive R/R GZL. Copyright: © Terao et al.Entities:
Keywords: CD30; brentuximab vedotin; gray zone lymphoma; refractory; relapsed
Year: 2021 PMID: 33936598 PMCID: PMC8082227 DOI: 10.3892/mco.2021.2287
Source DB: PubMed Journal: Mol Clin Oncol ISSN: 2049-9450