Literature DB >> 33930992

A new diarylhexane and two new diarylpropanols from the roots of Knema globularia.

Uraiwan Sriphana1, Chavi Yenjai2, Jittra Suthiwong3, Kitisak Poopasit2.   

Abstract

A new diarylhexane, kneglobularone B (1) and two new diarylpropanols, kneglobularols A - B (2 - 3) along with seven known compounds (4 - 10) were isolated and characterized from the roots of Knema globularia. It is the first time to find arylpropyl quinone (4) and isoflavone (8) in Myristicaceae family. In addition, 5 was found for the first time in Knema genus. Their structures were elucidated by UV, IR, MS, 1 D and 2 D NMR techniques. Compound 4 exhibited strong cytotoxicity against the NCI - H187 and MCF - 7 cell lines with IC50 values of 3.08 and 6.68 µg/mL, respectively.

Entities:  

Keywords:  Knema globularia; cytotoxicity; diarylhexane; diarylpropanol

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Year:  2020        PMID： 33930992     DOI： 10.1080/14786419.2020.1815736

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  2 in total

1.  Ethnomedicinal Plants in Herbal Remedies Used for Treatment of Skin Diseases by Traditional Healers in Songkhla Province, Thailand.

Authors:  Jongkon Saising; Katesarin Maneenoon; Oraphan Sakulkeo; Surasak Limsuwan; Friedrich Götz; Supayang Piyawan Voravuthikunchai
Journal:  Plants (Basel)       Date:  2022-03-25

2.  Knecorticosanones C-H from the fruits of Knema globularia (Lam.) warb.

Authors:  Chindawadee Chuenban; Aonnicha Sombatsri; Thurdpong Sribuhom; Chanakan Pornchoo; Auemduan Prawan; Sarawut Tontapha; Vittaya Amornkitbamrung; Chavi Yenjai
Journal:  RSC Adv       Date:  2021-01-20       Impact factor: 3.361
  2 in total

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