| Literature DB >> 33925382 |
Xiaoming Cao1, Liyuan Gu2, Shike Hu2, Aiman Mukhtar1, Kaiming Wu1.
Abstract
A lot of nanomaterials are using T1-T2 dual mode magnetic resonance (MR) contrast agents (CAs), but multilayer nanowire (NW) with iron (Fe) and manganese (Mn) as T1-T2 dual modal CAs has not been reported yet. Herein, we synthesized a Fe/Mn multilayer NW with an adjustable Fe layer, as T1-T2 dual-mode CAs. The relaxation performance of Fe/Mn multilayer NW was studied at 1.5 T. Results show that, when the length of the Fe layer is about 10 nm and the Mn is about 5 nm, the r1 value (21.8 mM-1s-1) and r2 value (74.8 mM-1s-1) of the Fe/Mn multilayer NW are higher than that of Mn NW (3.7 mM-1s-1) and Fe NW (59.3 mM-1s-1), respectively. We predict that our Fe/Mn multilayer NW could be used as T1-T2 dual mode MRI CAs in the near future.Entities:
Keywords: CAs; MRI; dual modal; nanowire; relaxation
Year: 2021 PMID: 33925382 DOI: 10.3390/ma14092238
Source DB: PubMed Journal: Materials (Basel) ISSN: 1996-1944 Impact factor: 3.623