Literature DB >> 33922907

Candida auris: A Quick Review on Identification, Current Treatments, and Challenges.

Lucia Černáková1, Maryam Roudbary2, Susana Brás3, Silva Tafaj4, Célia F Rodrigues5.   

Abstract

Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has a high rate of multidrug resistance and the occurrence of misleading identifications, and the ability of forming biofilms (naturally more resistant to drugs) has made treatments of C. auris infections highly difficult. This review intends to quickly illustrate the main issues in C. auris identification, available treatments and the associated mechanisms of resistance, and the novel and alternative treatment and drugs (natural and synthetic) that have been recently reported.

Entities:  

Keywords:  Candida auris; antifungal; biofilm; infection; novel therapy; resistance

Year:  2021        PMID: 33922907     DOI: 10.3390/ijms22094470

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN: 1422-0067            Impact factor:   5.923


  94 in total

1.  Candida auris: a global fungal public health threat.

Authors:  Jacques F Meis; Anuradha Chowdhary
Journal:  Lancet Infect Dis       Date:  2018-10-04       Impact factor: 25.071

2.  Direct Detection of Emergent Fungal Pathogen Candida auris in Clinical Skin Swabs by SYBR Green-Based Quantitative PCR Assay.

Authors:  D Joseph Sexton; Milena Kordalewska; Meghan L Bentz; Rory M Welsh; David S Perlin; Anastasia P Litvintseva
Journal:  J Clin Microbiol       Date:  2018-11-27       Impact factor: 5.948

3.  Molecular identification of Candida auris by PCR amplification of species-specific GPI protein-encoding genes.

Authors:  Alba Cecilia Ruiz-Gaitán; Jordan Fernández-Pereira; Eulogio Valentin; Maria Angeles Tormo-Mas; Elena Eraso; Javier Pemán; Piet W J de Groot
Journal:  Int J Med Microbiol       Date:  2018-07-08       Impact factor: 3.473

4.  Single-tube classical PCR for Candida auris and Candida haemulonii identification.

Authors:  Laura Theill; Catiana Dudiuk; Soraya Morales-Lopez; Indira Berrio; José Yesid Rodríguez; Adriana Marin; Soledad Gamarra; Guillermo Garcia-Effron
Journal:  Rev Iberoam Micol       Date:  2018-04-21       Impact factor: 1.044

5.  Multiple introductions and subsequent transmission of multidrug-resistant Candida auris in the USA: a molecular epidemiological survey.

Authors:  Nancy A Chow; Lalitha Gade; Sharon V Tsay; Kaitlin Forsberg; Jane A Greenko; Karen L Southwick; Patricia M Barrett; Janna L Kerins; Shawn R Lockhart; Tom M Chiller; Anastasia P Litvintseva
Journal:  Lancet Infect Dis       Date:  2018-10-04       Impact factor: 25.071

6.  Clade-specific chromosomal rearrangements and loss of subtelomeric adhesins in Candida auris.

Authors:  José F Muñoz; Rory M Welsh; Terrance Shea; Dhwani Batra; Lalitha Gade; Dakota Howard; Lori A Rowe; Jacques F Meis; Anastasia P Litvintseva; Christina A Cuomo
Journal:  Genetics       Date:  2021-05-17       Impact factor: 4.562

7.  Draft Genome Sequence of a Fluconazole-Resistant Candida auris Strain from a Candidemia Patient in India.

Authors:  Cheshta Sharma; Nitin Kumar; Jacques F Meis; Rajesh Pandey; Anuradha Chowdhary
Journal:  Genome Announc       Date:  2015-07-16

8.  Structural absorption by barbule microstructures of super black bird of paradise feathers.

Authors:  Dakota E McCoy; Teresa Feo; Todd Alan Harvey; Richard O Prum
Journal:  Nat Commun       Date:  2018-01-09       Impact factor: 14.919

9.  Rapid and Visual Detection of Trichinella Spp. Using a Lateral Flow Strip-Based Recombinase Polymerase Amplification (LF-RPA) Assay.

Authors:  Ting-Ting Li; Jin-Lei Wang; Nian-Zhang Zhang; Wen-Hui Li; Hong-Bin Yan; Li Li; Wan-Zhong Jia; Bao-Quan Fu
Journal:  Front Cell Infect Microbiol       Date:  2019-01-21       Impact factor: 5.293

10.  Increasing prevalence, molecular characterization and antifungal drug susceptibility of serial Candida auris isolates in Kuwait.

Authors:  Ziauddin Khan; Suhail Ahmad; Noura Al-Sweih; Leena Joseph; Wadha Alfouzan; Mohammad Asadzadeh
Journal:  PLoS One       Date:  2018-04-09       Impact factor: 3.240

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  10 in total

1.  Genome-wide analysis of PTR transporters in Candida species and their functional characterization in Candida auris.

Authors:  Rosy Khatoon; Suman Sharma; Rajendra Prasad; Andrew M Lynn; Amresh Prakash; Atanu Banerjee
Journal:  Appl Microbiol Biotechnol       Date:  2022-06-01       Impact factor: 4.813

2.  Commentary: Experimental Mouse Models of Invasive Candidiasis Caused by Candida auris and Other Medically Important Candida Species.

Authors:  Hong Xin
Journal:  J Cell Immunol       Date:  2022

Review 3.  Candida auris and other phylogenetically related species - a mini-review of the literature.

Authors:  Cristina Nicoleta Ciurea; Anca Delia Mare; Irina-Bianca Kosovski; Felicia Toma; Camelia Vintilă; Adrian Man
Journal:  Germs       Date:  2021-09-29

4.  Molecular Characterization of Candida auris Isolates at a Major Tertiary Care Center in Lebanon.

Authors:  Lina Reslan; George F Araj; Marc Finianos; Rima El Asmar; Jaroslav Hrabak; Ghassan Dbaibo; Ibrahim Bitar
Journal:  Front Microbiol       Date:  2022-01-25       Impact factor: 5.640

5.  A Polyclonal SELEX Aptamer Library Allows Differentiation of Candida albicans, C. auris and C. parapsilosis Cells from Human Dermal Fibroblasts.

Authors:  Katharina Kneißle; Markus Krämer; Ann-Kathrin Kissmann; Hu Xing; Franziska Müller; Valerie Amann; Reiner Noschka; Kay-Eberhard Gottschalk; Anil Bozdogan; Jakob Andersson; Tanja Weil; Barbara Spellerberg; Steffen Stenger; Frank Rosenau
Journal:  J Fungi (Basel)       Date:  2022-08-15

Review 6.  Marine Compounds with Anti-Candida sp. Activity: A Promised "Land" for New Antifungals.

Authors:  Anelise Maria Costa Vasconcelos Alves; Natália Cruz-Martins; Célia Fortuna Rodrigues
Journal:  J Fungi (Basel)       Date:  2022-06-25

7.  The rise of Candida auris: from unique traits to co-infection potential.

Authors:  Nadine B Egger; Katharina Kainz; Adina Schulze; Maria A Bauer; Frank Madeo; Didac Carmona-Gutierrez
Journal:  Microb Cell       Date:  2022-08-01

8.  Zinc(II), Palladium(II), and Metal-Free Phthalocyanines Bearing Nipagin-Functionalized Substituents against Candida auris and Selected Multidrug-Resistant Microbes.

Authors:  Daniel Ziental; Dariusz T Mlynarczyk; Emil Kolasinski; Emre Güzel; Jolanta Dlugaszewska; Łukasz Popenda; Stefan Jurga; Tomasz Goslinski; Lukasz Sobotta
Journal:  Pharmaceutics       Date:  2022-08-12       Impact factor: 6.525

Review 9.  Diagnosis and Treatment of Invasive Candidiasis.

Authors:  Natalia Barantsevich; Elena Barantsevich
Journal:  Antibiotics (Basel)       Date:  2022-05-26

10.  Candida Cell-Surface-Specific Monoclonal Antibodies Protect Mice against Candida auris Invasive Infection.

Authors:  Jonothan Rosario-Colon; Karen Eberle; Abby Adams; Evan Courville; Hong Xin
Journal:  Int J Mol Sci       Date:  2021-06-07       Impact factor: 5.923

  10 in total

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