Literature DB >> 33922326

Choosing the Right Partner for Medication Related Osteonecrosis of the Jaw: What Central European Dentists Know.

Emanuel Bruckmoser1, Miriam Palaoro2, Lukas Latzko2, Dagmar Schnabl3, Sabrina B Neururer4,5, Johannes Laimer2.   

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) is a side effect of antiresorptive drugs. In this online survey, the awareness and knowledge of dentists regarding MRONJ was evaluated, and potential implications for oncologists are discussed. Questionnaires were emailed to dentists from Germany, Austria, Switzerland, and South Tyrol to evaluate disease-related knowledge and management. In addition to the overall score, a separate score was calculated for knowledge (maximum score: 15 points) and management (maximum score: 6 points) questions, and 1197 valid replies with completed questionnaires were received. The mean overall score was 10.45 ± 3.97 points, the mean knowledge score was 7.68 ± 3.05 points, and the mean management score was 2.76 ± 1.77 points. Factors influencing the outcome of the overall score were age, specialization, continuous professional education, and the number of dental screening exams in patients before antiresorptive therapy. Due to the considerable lack of knowledge regarding MRONJ among dentists, MRONJ patients and subjects at risk should be guided towards specialists for dental screening, treatment, and follow-up. This is important from an oncologic point of view to avoid any delay for treatment start of antiresorptives, and to reveal a potentially emerging osteonecrosis at an early stage, thus, avoiding the need for interruption or even cancellation of antiresorptive therapy.

Entities:  

Keywords:  MRONJ; antiresorptive treatment; bisphosphonates; bone metastases; denosumab; dental oncology; medication-related osteonecrosis of the jaw

Year:  2021        PMID: 33922326     DOI: 10.3390/ijerph18094466

Source DB:  PubMed          Journal:  Int J Environ Res Public Health        ISSN: 1660-4601            Impact factor:   3.390


  20 in total

1.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

2.  Knowledge, practices, and opinions of ontario dentists when treating patients receiving bisphosphonates.

Authors:  Ahmed Alhussain; Sean Peel; Laura Dempster; Cameron Clokie; Amir Azarpazhooh
Journal:  J Oral Maxillofac Surg       Date:  2015-01-12       Impact factor: 1.895

3.  Workshop of European task force on medication-related osteonecrosis of the jaw-Current challenges.

Authors:  Morten Schiodt; Sven Otto; Stefano Fedele; Alberto Bedogni; Ourania Nicolatou-Galitis; Roman Guggenberger; Bente Brokstad Herlofson; Oliver Ristow; Thomas Kofod
Journal:  Oral Dis       Date:  2019-08-19       Impact factor: 3.511

4.  Surgical Treatment of Osteonecrosis of the Jaw: An Emerging Problem in the Era of Bisphosphonates.

Authors:  Kay Su Hung; Clifford Charles Sheckter; Dyani Gaudilliere; Paola Suarez; Catherine Curtin
Journal:  J Oral Maxillofac Surg       Date:  2020-01-07       Impact factor: 1.895

5.  Usefulness of advanced-platelet rich fibrin (A-PRF) and injectable-platelet rich fibrin (i-PRF) in the management of a massive medication-related osteonecrosis of the jaw (MRONJ): A 5-years follow-up case report.

Authors:  Amerigo Giudice; Alessandro Antonelli; Danila Muraca; Leonzio Fortunato
Journal:  Indian J Dent Res       Date:  2020 Sep-Oct

6.  Can Surgical Management Improve Resolution of Medication-Related Osteonecrosis of the Jaw at Early Stages? A Prospective Cohort Study.

Authors:  Amerigo Giudice; Selene Barone; Federica Diodati; Alessandro Antonelli; Riccardo Nocini; Maria Giulia Cristofaro
Journal:  J Oral Maxillofac Surg       Date:  2020-06-01       Impact factor: 1.895

7.  Osteonecrosis of the jaw related to non-antiresorptive medications: a systematic review.

Authors:  Ourania Nicolatou-Galitis; Maria Kouri; Erofili Papadopoulou; Emmanouil Vardas; Dimitra Galiti; Joel B Epstein; Sharon Elad; Giuseppina Campisi; Nikolaos Tsoukalas; Kivanc Bektas-Kayhan; Winston Tan; Jean-Jacques Body; Cesar Migliorati; Rajesh V Lalla
Journal:  Support Care Cancer       Date:  2018-10-23       Impact factor: 3.603

8.  American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update.

Authors:  Salvatore L Ruggiero; Thomas B Dodson; John Fantasia; Reginald Goodday; Tara Aghaloo; Bhoomi Mehrotra; Felice O'Ryan
Journal:  J Oral Maxillofac Surg       Date:  2014-05-05       Impact factor: 2.136

9.  A multicenter case registry study on medication-related osteonecrosis of the jaw in patients with advanced cancer.

Authors:  Morten Schiodt; Saroj Vadhan-Raj; Mark S Chambers; Ourania Nicolatou-Galitis; Constantinus Politis; Ruxandra Coropciuc; Stefano Fedele; Danielle Jandial; Jeffrey Zhang; Haijun Ma; Deborah P Saunders
Journal:  Support Care Cancer       Date:  2017-12-23       Impact factor: 3.603

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  1 in total

1.  Medication-Related Osteonecrosis of the Jaw in Dental Practice: A Retrospective Analysis of Data from the Milan Cohort.

Authors:  Cristina Mirelli; Sonia Marino; Andrea Bovio; Sara Pederielli; Cristina Dall'Agnola; Aldo Bruno Gianni; Roberto Biagi
Journal:  Dent J (Basel)       Date:  2022-05-19
  1 in total

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