Literature DB >> 3391630

Allopurinol kinetics after massive overdosage.

R E Ferner1, H A Simmonds, D N Bateman.   

Abstract

A 15-year-old girl with normal renal function took 75 tablets of allopurinol 300 mg. She did not suffer any ill-effects. Samples obtained over 84 h showed prolonged elimination of allopurinol, with a half-life of 3.6 h, and oxipurinol, with a half-life of 26 h.

Entities:  

Mesh:

Substances:

Year:  1988        PMID: 3391630     DOI: 10.1177/096032718800700313

Source DB:  PubMed          Journal:  Hum Toxicol        ISSN: 0144-5952


  2 in total

1.  Oxypurinol, allopurinol and allopurinol-1-riboside in plasma following an acute overdose of allopurinol in a patient with advanced chronic kidney disease.

Authors:  Diluk R W Kannangara; Darren M Roberts; Timothy J Furlong; Garry G Graham; Kenneth M Williams; Richard O Day
Journal:  Br J Clin Pharmacol       Date:  2012-05       Impact factor: 4.335

Review 2.  Risks and benefits of drugs used in the management and prevention of gout.

Authors:  P G Conaghan; R O Day
Journal:  Drug Saf       Date:  1994-10       Impact factor: 5.606

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.