Literature DB >> 33910190

Radiochromic film dosimetry for protons up to 10 MeV with EBT2, EBT3 and unlaminated EBT3 films.

Daniel Sanchez-Parcerisa1,2,3, Irene Sanz-García1, Paula Ibáñez1,2, Samuel España1,2,4, Andrea Espinosa1,2, Carolina Gutiérrez-Neira1,5,6, Alfonso López7, Juan Antonio Vera8, Alejandro Mazal8, Luis Mario Fraile1,2, José Manuel Udías1,2.   

Abstract

Passive dosimetry with radiochromic films is widely used in proton radiotherapy, both in clinical and scientific environments, thanks to its simplicity, high spatial resolution and dose-rate independence. However, film under-response for low-energy protons, the so-called linear-energy transfer (LET) quenching, must be accounted and corrected for. We perform a meta-analysis on existing film under-response data with EBT, EBT2 and EBT3 GAFchromic™ films and provide a common framework to integrate it, based on the calculation of dose-averaged LET in the active layer of the films. We also report on direct measurements with the 10 MeV proton beam at the Center for Microanalysis of Materials (CMAM) for EBT2, EBT3 and unlaminated EBT3 films, focusing on the 20-80 keVμm-1LET range, where previous data was scarce. Measured film relative efficiency (RE) values are in agreement with previously reported data from the literature. A model on film RE constructed with combined literature and own experimental values in the 5-80 keVμm-1LET range is presented, supporting the hypothesis of a linear decrease of RE with LET, with no remarkable differences between the three types of films analyzed.
© 2021 Institute of Physics and Engineering in Medicine.

Keywords:  EBT2; EBT3; LET quenching; dosimetry; protontherapy; radiochromic

Year:  2021        PMID: 33910190     DOI: 10.1088/1361-6560/abfc8d

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  1 in total

1.  In vivo production of fluorine-18 in a chicken egg tumor model of breast cancer for proton therapy range verification.

Authors:  Samuel España; Daniel Sánchez-Parcerisa; Paloma Bragado; Álvaro Gutiérrez-Uzquiza; Almudena Porras; Carolina Gutiérrez-Neira; Andrea Espinosa; Víctor V Onecha; Paula Ibáñez; Víctor Sánchez-Tembleque; José M Udías; Luis M Fraile
Journal:  Sci Rep       Date:  2022-04-30       Impact factor: 4.996

  1 in total

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