| Literature DB >> 33906149 |
Noel Lorenzo Villalba1, Abrar-Ahmad Zulfiqar2, Maria Belén Alonso Ortiz3, Xavier Jannot2, Anezka Syrovatkova2, Emmanuel Andres2.
Abstract
We report the case of an 86-year-old man presenting with a spontaneous hematoma in the left iliac muscle and previous diagnosis of colon cancer in 1998 (stage pT3N0M0) treated with transverse colectomy and considered in complete remission. After a complete study, it was possible to identify the presence of Factor VIII inhibitors antibodies that confirmed the presence of acquired hemophilia. During hospitalization the patient presented a lower gastrointestinal bleeding leading to the diagnosis of recurrence of a previously treated colorectal adenocarcinoma. He responded to initial therapy with systemic corticoids and anti-inhibitory coagulant complex which includes activated VII Factor [FEIBA].Entities:
Keywords: acquired hemophilia; anti Factor VIII antibodies; spontaneous hematoma
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Year: 2021 PMID: 33906149
Source DB: PubMed Journal: Medicina (B Aires) ISSN: 0025-7680 Impact factor: 0.653