Literature DB >> 33906149

[Acquired hemophilia as the initial manifestation of colorectal cancer's recurrence].

Noel Lorenzo Villalba1, Abrar-Ahmad Zulfiqar2, Maria Belén Alonso Ortiz3, Xavier Jannot2, Anezka Syrovatkova2, Emmanuel Andres2.   

Abstract

We report the case of an 86-year-old man presenting with a spontaneous hematoma in the left iliac muscle and previous diagnosis of colon cancer in 1998 (stage pT3N0M0) treated with transverse colectomy and considered in complete remission. After a complete study, it was possible to identify the presence of Factor VIII inhibitors antibodies that confirmed the presence of acquired hemophilia. During hospitalization the patient presented a lower gastrointestinal bleeding leading to the diagnosis of recurrence of a previously treated colorectal adenocarcinoma. He responded to initial therapy with systemic corticoids and anti-inhibitory coagulant complex which includes activated VII Factor [FEIBA].

Entities:  

Keywords:  acquired hemophilia; anti Factor VIII antibodies; spontaneous hematoma

Mesh:

Substances:

Year:  2021        PMID: 33906149

Source DB:  PubMed          Journal:  Medicina (B Aires)        ISSN: 0025-7680            Impact factor:   0.653


  1 in total

1.  [Acquired hemophilia]

Authors:  Martín Milanesio; Aldo Hugo Tabares; Gastón Andrés Caeiro; Julieta Olmedo; Ana Romina Montivero
Journal:  Rev Fac Cien Med Univ Nac Cordoba       Date:  2022-03-07
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.