| Literature DB >> 33902582 |
Zhenming Jiang1, Yuxi Zhang2,3, Xi Chen4, Pingeng Wu1, Dong Chen5.
Abstract
Entities:
Year: 2021 PMID: 33902582 PMCID: PMC8077683 DOI: 10.1186/s12935-021-01945-5
Source DB: PubMed Journal: Cancer Cell Int ISSN: 1475-2867 Impact factor: 5.722
Fig. 6Overexpressed miR-129-5p or silencing ZIC2 inhibits PCa cell migration and invasion. DU-145 cells were treated with miR-129-5p mimic, miR-129-5p inhibitor or/and si-ZIC2. a Cell migration within each group (× 200). b The migration cell number. c The cell invasion (× 200). d The invasive cell number in each group. *p < 0.05 vs. the blank and NC groups. The data are summarized as mean ± standard deviation and compared using one-way analysis of variance. The experiment was repeated three times and the average value was obtained
Fig. 7Angiogenesis of PCa cells is blocked by overexpressed miR-129-5p or down-regulated ZIC2. DU-145 cells were treated with miR-129-5p mimic, miR-129-5p inhibitor or/and si-ZIC2. a The angiogenesis in each group; b the angiogenesis indexes in each group; c the protein expression of VEGF and CD31 in each group; d the statistical analysis of c. *p < 0.05 vs. the blank and NC groups. The data are summarized as mean ± standard deviation. The experiment was repeated three times and the data were compared using the one-way analysis of variance. VEGF vascular endothelial growth factor, GAPDH glyceraldehyde-3-phosphate dehydrogenase