Literature DB >> 33900491

Organoid: a powerful tool to study lung regeneration and disease.

Tiantian Lu1, Yiyuan Cao1, Peng Zhao1, Shengxi Shen1, Ying Xi2.   

Abstract

Organoids are three-dimensional self-organizing structures formed by adult tissue stem cells or pluripotent stem cells. They recapitulate cell-cell, cell-niche interactions in tissue development, homeostasis, regeneration and disease, and provide an in vitro model for drug screening. This review summarizes the recent advances of organoid cultures derived from adult lung stem cells and human pluripotent stem cells, especially focusing on the organoids of the distal airway stem/progenitor cells. We also discuss the applications of organoids in studying lung regeneration and pulmonary diseases, including pulmonary fibrosis, airway diseases and Coronavirus disease 2019 (COVID-19).

Entities:  

Year:  2021        PMID： 33900491     DOI： 10.1186/s13619-021-00082-8

Source DB:  PubMed          Journal:  Cell Regen        ISSN： 2045-9769


  55 in total

1.  Type 2 alveolar cells are stem cells in adult lung.

Authors:  Christina E Barkauskas; Michael J Cronce; Craig R Rackley; Emily J Bowie; Douglas R Keene; Barry R Stripp; Scott H Randell; Paul W Noble; Brigid L M Hogan
Journal:  J Clin Invest       Date:  2013-06-10       Impact factor: 14.808

2.  Number and proliferation of basal and parabasal cells in normal human airway epithelium.

Authors:  J E Boers; A W Ambergen; F B Thunnissen
Journal:  Am J Respir Crit Care Med       Date:  1998-06       Impact factor: 21.405

3.  Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung.

Authors:  Henry Danahay; Angelica D Pessotti; Julie Coote; Brooke E Montgomery; Donghui Xia; Aaron Wilson; Haidi Yang; Zhao Wang; Luke Bevan; Chris Thomas; Stephanie Petit; Anne London; Peter LeMotte; Arno Doelemeyer; Germán L Vélez-Reyes; Paula Bernasconi; Christy J Fryer; Matt Edwards; Paola Capodieci; Amy Chen; Marc Hild; Aron B Jaffe
Journal:  Cell Rep       Date:  2014-12-31       Impact factor: 9.423

Review 4.  Lung organoids: current uses and future promise.

Authors:  Christina E Barkauskas; Mei-I Chung; Bryan Fioret; Xia Gao; Hiroaki Katsura; Brigid L M Hogan
Journal:  Development       Date:  2017-03-15       Impact factor: 6.868

5.  Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice.

Authors:  Harold A Chapman; Xiaopeng Li; Jonathan P Alexander; Alexis Brumwell; Walter Lorizio; Kevin Tan; Arnoud Sonnenberg; Ying Wei; Thiennu H Vu
Journal:  J Clin Invest       Date:  2011-06-23       Impact factor: 14.808

6.  Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury.

Authors:  Huaiyong Chen; Keitaro Matsumoto; Brian L Brockway; Craig R Rackley; Jiurong Liang; Joo-Hyeon Lee; Dianhua Jiang; Paul W Noble; Scott H Randell; Carla F Kim; Barry R Stripp
Journal:  Stem Cells       Date:  2012-09       Impact factor: 6.277

7.  A functional CFTR assay using primary cystic fibrosis intestinal organoids.

Authors:  Johanna F Dekkers; Caroline L Wiegerinck; Hugo R de Jonge; Inez Bronsveld; Hettie M Janssens; Karin M de Winter-de Groot; Arianne M Brandsma; Nienke W M de Jong; Marcel J C Bijvelds; Bob J Scholte; Edward E S Nieuwenhuis; Stieneke van den Brink; Hans Clevers; Cornelis K van der Ent; Sabine Middendorp; Jeffrey M Beekman
Journal:  Nat Med       Date:  2013-06-02       Impact factor: 53.440

8.  A three-dimensional model of human lung development and disease from pluripotent stem cells.

Authors:  Ya-Wen Chen; Sarah Xuelian Huang; Ana Luisa Rodrigues Toste de Carvalho; Siu-Hong Ho; Mohammad Naimul Islam; Stefano Volpi; Luigi D Notarangelo; Michael Ciancanelli; Jean-Laurent Casanova; Jahar Bhattacharya; Alice F Liang; Laura M Palermo; Matteo Porotto; Anne Moscona; Hans-Willem Snoeck
Journal:  Nat Cell Biol       Date:  2017-04-24       Impact factor: 28.824

Review 9.  The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future.

Authors:  Maria C Basil; Jeremy Katzen; Anna E Engler; Minzhe Guo; Michael J Herriges; Jaymin J Kathiriya; Rebecca Windmueller; Alexandra B Ysasi; William J Zacharias; Hal A Chapman; Darrell N Kotton; Jason R Rock; Hans-Willem Snoeck; Gordana Vunjak-Novakovic; Jeffrey A Whitsett; Edward E Morrisey
Journal:  Cell Stem Cell       Date:  2020-04-02       Impact factor: 24.633

10.  Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung.

Authors:  Monica Cassandras; Chaoqun Wang; Jaymin Kathiriya; Tatsuya Tsukui; Peri Matatia; Michael Matthay; Paul Wolters; Ari Molofsky; Dean Sheppard; Hal Chapman; Tien Peng
Journal:  Nat Cell Biol       Date:  2020-10-12       Impact factor: 28.824
View more
  4 in total

Review 1.  Biomechanical Force and Cellular Stiffness in Lung Fibrosis.

Authors:  Richard S Nho; Megan N Ballinger; Mauricio M Rojas; Samir N Ghadiali; Jeffrey C Horowitz
Journal:  Am J Pathol       Date:  2022-02-17       Impact factor: 5.770

Review 2.  Three-Dimensional Cell Culture Models to Study Respiratory Virus Infections Including COVID-19.

Authors:  Aya Harb; Mohammad Fakhreddine; Hassan Zaraket; Fatima A Saleh
Journal:  Biomimetics (Basel)       Date:  2021-12-25

Review 3.  Tumor organoids: synergistic applications, current challenges, and future prospects in cancer therapy.

Authors:  Jingjing Qu; Farhin Shaheed Kalyani; Li Liu; Tianli Cheng; Lijun Chen
Journal:  Cancer Commun (Lond)       Date:  2021-10-29

Review 4.  Modeling Human Organ Development and Diseases With Fetal Tissue-Derived Organoids.

Authors:  Jianqing Liang; Xinyang Li; Yateng Dong; Bing Zhao
Journal:  Cell Transplant       Date:  2022 Jan-Dec       Impact factor: 4.139
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.