Marcel E Salive1, Jerry Suls2, Tilda Farhat3, Carrie N Klabunde4. 1. Geriatrics Branch, National Institute on Aging, Bethesda, MD. 2. Behavioral Research Program, National Cancer Institute, Currently at Feinstein Institutes for Medical Research/Northwell Health, New York City, NY. 3. Office of Science Policy, Planning, Evaluation, and Reporting, National Institute on Minority Health and Health Disparities, National Institutes of Health. 4. Disease Prevention, Office of Disease Prevention, National Institutes of Health, Bethesda, MD.
Abstract
BACKGROUND: Multimorbidity, the co-occurrence of 2 or more chronic diseases, is more common than having a single chronic disease, especially among persons age 65 years and older. The routine measurement of multimorbidity can facilitate a better understanding of potential causes and interactions and promote more effective treatment and improved outcomes. OBJECTIVES: To present a multimorbidity research framework and identify gaps in the research literature related to multimorbidity. DESIGN: In preparation for an expert panel workshop convened in September 2018, planning committee members reviewed the literature and developed a guiding framework that informed the selection of topics and speakers. RESULTS: The framework, grounded in a patient-centered approach, incorporates the concept of concordant and discordant comorbidity, and includes potential causes, interactions, and outcomes. This work informed workshop presentations and discussion related to identifying and selecting the best available multimorbidity instruments and determining future research needs. CONCLUSIONS: Multimorbidity research can be advanced by addressing gaps in study design and target populations, and by increasing attention to universal outcome measurement.
BACKGROUND: Multimorbidity, the co-occurrence of 2 or more chronic diseases, is more common than having a single chronic disease, especially among persons age 65 years and older. The routine measurement of multimorbidity can facilitate a better understanding of potential causes and interactions and promote more effective treatment and improved outcomes. OBJECTIVES: To present a multimorbidity research framework and identify gaps in the research literature related to multimorbidity. DESIGN: In preparation for an expert panel workshop convened in September 2018, planning committee members reviewed the literature and developed a guiding framework that informed the selection of topics and speakers. RESULTS: The framework, grounded in a patient-centered approach, incorporates the concept of concordant and discordant comorbidity, and includes potential causes, interactions, and outcomes. This work informed workshop presentations and discussion related to identifying and selecting the best available multimorbidity instruments and determining future research needs. CONCLUSIONS: Multimorbidity research can be advanced by addressing gaps in study design and target populations, and by increasing attention to universal outcome measurement.
Authors: Michael Von Korff; Wayne J Katon; Elizabeth H B Lin; Paul Ciechanowski; Do Peterson; Evette J Ludman; Bessie Young; Carolyn M Rutter Journal: BMJ Date: 2011-11-10
Authors: Joshua C Denny; Joni L Rutter; David B Goldstein; Anthony Philippakis; Jordan W Smoller; Gwynne Jenkins; Eric Dishman Journal: N Engl J Med Date: 2019-08-15 Impact factor: 176.079
Authors: Jerry Suls; Elizabeth A Bayliss; Jay Berry; Arlene S Bierman; Elizabeth A Chrischilles; Tilda Farhat; Martin Fortin; Siran M Koroukian; Ana Quinones; Jeffrey H Silber; Brian W Ward; Melissa Wei; Deborah Young-Hyman; Carrie N Klabunde Journal: Med Care Date: 2021-08-01 Impact factor: 3.178
Authors: Songprod Jonathan Lorgunpai; Marianthe Grammas; David S H Lee; Gail McAvay; Peter Charpentier; Mary E Tinetti Journal: PLoS One Date: 2014-02-25 Impact factor: 3.240
Authors: Jerry Suls; Marcel E Salive; Siran M Koroukian; Farrokh Alemi; Jeffrey H Silber; Gabi Kastenmüller; Carrie N Klabunde Journal: J Am Geriatr Soc Date: 2022-06-14 Impact factor: 7.538
Authors: Claire B Rosen; Sanford E Roberts; Chris J Wirtalla; Omar I Ramadan; Luke J Keele; Elinore J Kaufman; Scott D Halpern; Rachel R Kelz Journal: J Am Coll Surg Date: 2022-10-17 Impact factor: 6.532