Literature DB >> 3389652

Carcinogenicity of vinyl chloride in Sprague-Dawley rats after prenatal and postnatal exposure.

C Maltoni1, G Cotti.   

Abstract

Vinyl chloride was administered by inhalation, 7 hours daily, 5 days weekly, at concentrations of 2500 and 0 ppm, to Sprague-Dawley rats. The treatment was started on 13-week-old breeders and male and female offspring (12-day embryos). The breeders and part of the offspring were exposed for 104 weeks; the other part of the offspring was exposed for 15 weeks only. Under the experimental conditions, vinyl chloride caused an exceptionally high incidence of brain neuroblastomas, liver angiosarcomas, and hepatocarcinomas. The age at start and/or length of treatment may affect the onset of these tumors in different ways.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3389652     DOI： 10.1111/j.1749-6632.1988.tb30108.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  9 in total

Review 1.  The endogenous exposome.

Authors:  Jun Nakamura; Esra Mutlu; Vyom Sharma; Leonard Collins; Wanda Bodnar; Rui Yu; Yongquan Lai; Benjamin Moeller; Kun Lu; James Swenberg
Journal:  DNA Repair (Amst)       Date:  2014-04-24

2.  A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-Oxoethyl)guanine in sprague-dawley rats.

Authors:  Esra Mutlu; Yo-Chan Jeong; Leonard B Collins; Amy-Joan L Ham; Patricia B Upton; Gary Hatch; Darrell Winsett; Paul Evansky; James A Swenberg
Journal:  Chem Res Toxicol       Date:  2012-01-24       Impact factor: 3.739

3.  A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.

Authors:  Isaac A Chaim; Alycia Gardner; Jie Wu; Teruaki Iyama; David M Wilson; Leona D Samson
Journal:  Nucleic Acids Res       Date:  2017-04-07       Impact factor: 16.971

4.  Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC.

Authors:  Esra Mutlu; Leonard B Collins; Matthew D Stout; Patricia B Upton; Laura R Daye; Darrell Winsett; Gary Hatch; Paul Evansky; James A Swenberg
Journal:  Chem Res Toxicol       Date:  2010-09-20       Impact factor: 3.739

Review 5.  The role of chemical, physical, or viral exposures and health factors in neurocarcinogenesis: implications for epidemiologic studies of brain tumors.

Authors:  M P Berleur; S Cordier
Journal:  Cancer Causes Control       Date:  1995-05       Impact factor: 2.506

Review 6.  Scientific considerations for evaluating cancer bioassays conducted by the Ramazzini Institute.

Authors:  Jeffrey S Gift; Jane C Caldwell; Jennifer Jinot; Marina V Evans; Ila Cote; John J Vandenberg
Journal:  Environ Health Perspect       Date:  2013-09-17       Impact factor: 9.031

Review 7.  Non‑infective occupational risk factors for hepatocellular carcinoma: A review (Review).

Authors:  Caterina Ledda; Carla Loreto; Christian Zammit; Andrea Marconi; Lucrezia Fago; Serena Matera; Valentina Costanzo; Giovanni Fuccio Sanzà; Stefano Palmucci; Margherita Ferrante; Chiara Costa; Concettina Fenga; Antonio Biondi; Cristoforo Pomara; Venerando Rapisarda
Journal:  Mol Med Rep       Date:  2016-12-14       Impact factor: 2.952

8.  Making the Difference in Occupational Health: Three Original and Significant Cases Presented at ICOH Congresses in the 20th Century.

Authors:  Sergio Iavicoli; Antonio Valenti; Caterina Barillari; Grazia Fortuna; Valeria Boccuni; Francesco Carnevale; Michele A Riva; Seong-Kyu Kang; Luigi Tomassini
Journal:  Saf Health Work       Date:  2020-04-02

9.  The fifth plot of the Carcinogenic Potency Database: results of animal bioassays published in the general literature through 1988 and by the National Toxicology Program through 1989.

Authors:  L S Gold; N B Manley; T H Slone; G B Garfinkel; L Rohrbach; B N Ames
Journal:  Environ Health Perspect       Date:  1993-04       Impact factor: 9.031
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.