| Literature DB >> 3389568 |
B M Doorley1, S J Waters, R C Terrell, J L Robinson.
Abstract
The minimum alveolar concentration (MAC) of I-653 was determined in six beagle dogs and four New Zealand white rabbits. The MAC values (+/- SD) were 7.2 +/- 1.0 atm % for dogs and 8.9 +/- 0.3 atm % for rabbits. Comparison of these results with published MAC values for other anesthetics indicate that I-653 is one-third to one-eighth as potent as currently available volatile anesthetics (enflurane, isoflurane, and halothane). From these data and previous reports, human MAC was projected to be approximately 5.1 atm %.Entities:
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Year: 1988 PMID: 3389568 DOI: 10.1097/00000542-198807000-00013
Source DB: PubMed Journal: Anesthesiology ISSN: 0003-3022 Impact factor: 7.892