Literature DB >> 33893424

Slow to heal or slow to diagnose cancer?

Charlotte A Richards1, Alice Cameron2, John Collin3, Ceri W Hughes3, Barry G Main4.   

Abstract

There are around 8,500 new cases of oral squamous cell carcinoma (SCC) diagnosed in the UK each year and the incidence appears to be increasing. Although surgical and non-surgical treatment options have improved significantly in the last few decades, five-year survival has not, with an average five-year survival of 56% in the UK. Providing patients have access, there are frequent opportunities for oral cancer screening by their general dental practitioner. We present two cases of SCC managed in our department, both of whom were referred following a protracted period of review in general dental practice, where the initial 'benign diagnoses' were not re-evaluated during this time. This delay can considerably impact on patient outcomes, including survival. We outline each patient's clinical course, and key learning points to help dental practitioners detect lesions that require prompt referral to the oral and maxillofacial service for urgent investigation.

Entities:  

Mesh:

Year:  2021        PMID: 33893424      PMCID: PMC8063191          DOI: 10.1038/s41415-021-2837-y

Source DB:  PubMed          Journal:  Br Dent J        ISSN: 0007-0610            Impact factor:   1.626


  6 in total

1.  The synergistic effect of tobacco and alcohol consumption on oral squamous cell carcinoma: a systematic review and meta-analysis.

Authors:  Fernanda Weber Mello; Gilberto Melo; Júlia Jacoby Pasetto; Carolina Amália Barcellos Silva; Saman Warnakulasuriya; Elena Riet Correa Rivero
Journal:  Clin Oral Investig       Date:  2019-05-20       Impact factor: 3.573

2.  The pathology of oral cancer.

Authors:  P M Speight; P M Farthing
Journal:  Br Dent J       Date:  2018-11-09       Impact factor: 1.626

3.  Mouth cancer: presentation, detection and referral in primary dental care.

Authors:  M A O Lewis
Journal:  Br Dent J       Date:  2018-11-09       Impact factor: 1.626

4.  Diagnosis and referral delays in primary care for oral squamous cell cancer: a systematic review.

Authors:  Ciaran Grafton-Clarke; Kai Wen Chen; Jane Wilcock
Journal:  Br J Gen Pract       Date:  2018-11-19       Impact factor: 5.386

5.  The relative length of the patient and the primary care interval in patients with 28 common and rarer cancers.

Authors:  G Lyratzopoulos; C L Saunders; G A Abel; S McPhail; R D Neal; J Wardle; G P Rubin
Journal:  Br J Cancer       Date:  2015-03-31       Impact factor: 7.640

6.  The changing aetiology of head and neck squamous cell cancer: A tale of three cancers?

Authors:  S J Thomas; C M Penfold; A Waylen; A R Ness
Journal:  Clin Otolaryngol       Date:  2018-06-13       Impact factor: 2.597

  6 in total
  1 in total

1.  Effect of different doses of apatinib mesylate combined with chemotherapy on advanced oral cancer.

Authors:  Wei Yan; Jiaxuan Yan; Yong Chen; Qiang Li; Yanjun Guo
Journal:  Am J Transl Res       Date:  2021-12-15       Impact factor: 4.060

  1 in total

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