| Literature DB >> 33893283 |
Sebastian Pirch1,2, Felix Müller1,2, Eugenia Iofinova1, Julia Pazmandi1,2,3, Christiane V R Hütter1,2, Martin Chiettini1,2, Celine Sin1,2, Kaan Boztug1,3,4,5,6, Iana Podkosova7, Hannes Kaufmann7, Jörg Menche8,9,10.
Abstract
Networks provide a powerful representation of interacting components within complex systems, making them ideal for visually and analytically exploring big data. However, the size and complexity of many networks render static visualizations on typically-sized paper or screens impractical, resulting in proverbial 'hairballs'. Here, we introduce a Virtual Reality (VR) platform that overcomes these limitations by facilitating the thorough visual, and interactive, exploration of large networks. Our platform allows maximal customization and extendibility, through the import of custom code for data analysis, integration of external databases, and design of arbitrary user interface elements, among other features. As a proof of concept, we show how our platform can be used to interactively explore genome-scale molecular networks to identify genes associated with rare diseases and understand how they might contribute to disease development. Our platform represents a general purpose, VR-based data exploration platform for large and diverse data types by providing an interface that facilitates the interaction between human intuition and state-of-the-art analysis methods.Entities:
Year: 2021 PMID: 33893283 DOI: 10.1038/s41467-021-22570-w
Source DB: PubMed Journal: Nat Commun ISSN: 2041-1723 Impact factor: 14.919