Literature DB >> 33890208

Management of sepsis and septic shock in the emergency department.

Francesco Gavelli1,2, Luigi Mario Castello3,4, Gian Carlo Avanzi3,4.   

Abstract

Early management of sepsis and septic shock is crucial for patients' prognosis. As the Emergency Department (ED) is the place where the first medical contact for septic patients is likely to occur, emergency physicians play an essential role in the early phases of patient management, which consists of accurate initial diagnosis, resuscitation, and early antibiotic treatment. Since the issuing of the Surviving Sepsis Campaign guidelines in 2016, several studies have been published on different aspects of sepsis management, adding a substantial amount of new information on the pathophysiology and treatment of sepsis and septic shock. In light of this emerging evidence, the present narrative review provides a comprehensive account of the recent advances in septic patient management in the ED.

Entities:  

Keywords:  Antibiotic therapy; Emergency medicine; Fluid resuscitation; Preload responsiveness; Vasopressors

Year:  2021        PMID: 33890208     DOI: 10.1007/s11739-021-02735-7

Source DB:  PubMed          Journal:  Intern Emerg Med        ISSN: 1828-0447            Impact factor:   3.397


  105 in total

1.  The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Authors:  Mervyn Singer; Clifford S Deutschman; Christopher Warren Seymour; Manu Shankar-Hari; Djillali Annane; Michael Bauer; Rinaldo Bellomo; Gordon R Bernard; Jean-Daniel Chiche; Craig M Coopersmith; Richard S Hotchkiss; Mitchell M Levy; John C Marshall; Greg S Martin; Steven M Opal; Gordon D Rubenfeld; Tom van der Poll; Jean-Louis Vincent; Derek C Angus
Journal:  JAMA       Date:  2016-02-23       Impact factor: 56.272

2.  Hypernatremia and moderate-to-severe hyponatremia are independent predictors of mortality in septic patients at emergency department presentation: A sub-group analysis of the need-speed trial.

Authors:  Luigi Mario Castello; Francesco Gavelli; Marco Baldrighi; Livia Salmi; Filippo Mearelli; Nicola Fiotti; Filippo Patrucco; Mattia Bellan; Pier Paolo Sainaghi; Giulia Ronzoni; Salvatore Di Somma; Enrico Lupia; Maria Lorenza Muiesan; Gianni Biolo; Gian Carlo Avanzi
Journal:  Eur J Intern Med       Date:  2020-11-05       Impact factor: 4.487

3.  Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Authors:  Andrew Rhodes; Laura E Evans; Waleed Alhazzani; Mitchell M Levy; Massimo Antonelli; Ricard Ferrer; Anand Kumar; Jonathan E Sevransky; Charles L Sprung; Mark E Nunnally; Bram Rochwerg; Gordon D Rubenfeld; Derek C Angus; Djillali Annane; Richard J Beale; Geoffrey J Bellinghan; Gordon R Bernard; Jean-Daniel Chiche; Craig Coopersmith; Daniel P De Backer; Craig J French; Seitaro Fujishima; Herwig Gerlach; Jorge Luis Hidalgo; Steven M Hollenberg; Alan E Jones; Dilip R Karnad; Ruth M Kleinpell; Younsuck Koh; Thiago Costa Lisboa; Flavia R Machado; John J Marini; John C Marshall; John E Mazuski; Lauralyn A McIntyre; Anthony S McLean; Sangeeta Mehta; Rui P Moreno; John Myburgh; Paolo Navalesi; Osamu Nishida; Tiffany M Osborn; Anders Perner; Colleen M Plunkett; Marco Ranieri; Christa A Schorr; Maureen A Seckel; Christopher W Seymour; Lisa Shieh; Khalid A Shukri; Steven Q Simpson; Mervyn Singer; B Taylor Thompson; Sean R Townsend; Thomas Van der Poll; Jean-Louis Vincent; W Joost Wiersinga; Janice L Zimmerman; R Phillip Dellinger
Journal:  Crit Care Med       Date:  2017-03       Impact factor: 7.598

4.  The Surviving Sepsis Campaign Bundle: 2018 Update.

Authors:  Mitchell M Levy; Laura E Evans; Andrew Rhodes
Journal:  Crit Care Med       Date:  2018-06       Impact factor: 7.598

5.  Prospective evaluation of the quickSOFA score as a screening for sepsis in the emergency department.

Authors:  Monika Loritz; Hans-Jörg Busch; Thomas Helbing; Katrin Fink
Journal:  Intern Emerg Med       Date:  2020-02-08       Impact factor: 3.397

6.  Derivation and Validation of a Biomarker-Based Clinical Algorithm to Rule Out Sepsis From Noninfectious Systemic Inflammatory Response Syndrome at Emergency Department Admission: A Multicenter Prospective Study.

Authors:  Filippo Mearelli; Nicola Fiotti; Carlo Giansante; Chiara Casarsa; Daniele Orso; Marco De Helmersen; Nicola Altamura; Maurizio Ruscio; Luigi Mario Castello; Efrem Colonetti; Rossella Marino; Giulia Barbati; Andrea Bregnocchi; Claudio Ronco; Enrico Lupia; Giuseppe Montrucchio; Maria Lorenza Muiesan; Salvatore Di Somma; Gian Carlo Avanzi; Gianni Biolo
Journal:  Crit Care Med       Date:  2018-09       Impact factor: 7.598

7.  The Role of Osteopontin as a Diagnostic and Prognostic Biomarker in Sepsis and Septic Shock.

Authors:  Luigi Mario Castello; Marco Baldrighi; Luca Molinari; Livia Salmi; Vincenzo Cantaluppi; Rosanna Vaschetto; Greta Zunino; Marco Quaglia; Mattia Bellan; Francesco Gavelli; Paolo Navalesi; Gian Carlo Avanzi; Annalisa Chiocchetti
Journal:  Cells       Date:  2019-02-18       Impact factor: 6.600

8.  Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients.

Authors:  Elliott D Crouser; Joseph E Parrillo; Christopher W Seymour; Derek C Angus; Keri Bicking; Vincent G Esguerra; Octavia M Peck-Palmer; Robert T Magari; Mark W Julian; Jennifer M Kleven; Paarth J Raj; Gabrielle Procopio; Diana Careaga; Liliana Tejidor
Journal:  Crit Care Med       Date:  2019-08       Impact factor: 7.598

9.  Circulating bioactive adrenomedullin as a marker of sepsis, septic shock and critical illness.

Authors:  Oscar H M Lundberg; Maria Lengquist; Martin Spångfors; Martin Annborn; Deborah Bergmann; Janin Schulte; Helena Levin; Olle Melander; Attila Frigyesi; Hans Friberg
Journal:  Crit Care       Date:  2020-11-04       Impact factor: 9.097

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  3 in total

1.  Pulsed Electromagnetic Field (PEMF) Treatment Reduces Lipopolysaccharide-Induced Septic Shock in Mice.

Authors:  Chang-Gun Lee; Chanoh Park; Soonjae Hwang; Ju-Eun Hong; Minjeong Jo; Minseob Eom; Yongheum Lee; Ki-Jong Rhee
Journal:  Int J Mol Sci       Date:  2022-05-18       Impact factor: 6.208

2.  Combination of Prehospital NT-proBNP with qSOFA and NEWS to Predict Sepsis and Sepsis-Related Mortality.

Authors:  Francisco Martín-Rodríguez; Laura Melero-Guijarro; Guillermo J Ortega; Ancor Sanz-García; Teresa de la Torre de Dios; Jesús Álvarez Manzanares; José L Martín-Conty; Miguel A Castro Villamor; Juan F Delgado Benito; Raúl López-Izquierdo
Journal:  Dis Markers       Date:  2022-02-23       Impact factor: 3.434

Review 3.  Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options.

Authors:  Di Liu; Si-Yuan Huang; Jian-Hui Sun; Hua-Cai Zhang; Qing-Li Cai; Chu Gao; Li Li; Ju Cao; Fang Xu; Yong Zhou; Cha-Xiang Guan; Sheng-Wei Jin; Jin Deng; Xiang-Ming Fang; Jian-Xin Jiang; Ling Zeng
Journal:  Mil Med Res       Date:  2022-10-09
  3 in total

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