Literature DB >> 33888647

Diabetic Nephropathy - a Review of Risk Factors, Progression, Mechanism, and Dietary Management.

Vijayakumar Natesan1, Sung-Jin Kim2.   

Abstract

Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is intended to understand the nature of DN risk factors, progression, effects of glycemic levels, and stages of DN. We also explored the novel diagnostic and therapeutic approaches for DN such as gene therapy and stem cell treatments.

Entities:  

Keywords:  Diabetic nephropathy; Hyperglycemia; Kidney disease; Novel drugs

Year:  2021        PMID: 33888647     DOI: 10.4062/biomolther.2020.204

Source DB:  PubMed          Journal:  Biomol Ther (Seoul)        ISSN: 1976-9148            Impact factor:   4.634


  6 in total

Review 1.  Metabolic Bone Diseases and New Drug Developments.

Authors:  Vijayakumar Natesan; Sung-Jin Kim
Journal:  Biomol Ther (Seoul)       Date:  2022-03-28       Impact factor: 4.231

2.  The clinical efficacy and safety of dapagliflozin in patients with diabetic nephropathy.

Authors:  Ying Huang; Wen Lu; Hongyun Lu
Journal:  Diabetol Metab Syndr       Date:  2022-03-29       Impact factor: 3.320

Review 3.  The Nicotinamide/Streptozotocin Rodent Model of Type 2 Diabetes: Renal Pathophysiology and Redox Imbalance Features.

Authors:  Liang-Jun Yan
Journal:  Biomolecules       Date:  2022-09-02

4.  Peripheral Blood circRNA Microarray Profiling Identities hsa_circ_0001831 and hsa_circ_0000867 as Two Novel circRNA Biomarkers for Early Type 2 Diabetic Nephropathy.

Authors:  Keke Zhang; Xinxing Wan; Md Asaduzzaman Khan; Xiaoying Sun; Xuan Yi; Zhouqi Wang; Ke Chen; Lin Peng
Journal:  Diabetes Metab Syndr Obes       Date:  2022-09-10       Impact factor: 3.249

5.  Analysis of the Renal Protection and Antioxidative Stress Effects of Panax notoginseng Saponins in Diabetic Nephropathy Mice.

Authors:  Wei Mi; Min Yu; Shuying Yin; Yuhan Ji; Tala Shi; Ning Li
Journal:  J Immunol Res       Date:  2022-10-05       Impact factor: 4.493

6.  Efficacy and safety of eplerenone treatment for patients with diabetic nephropathy: A meta-analysis.

Authors:  Honglei Hu; Xiaodong Zhao; Xingqian Jin; Shujuan Wang; Wenlong Liang; Xiangguo Cong
Journal:  PLoS One       Date:  2022-03-24       Impact factor: 3.240

  6 in total

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