Literature DB >> 33886575

What gaps remain in the HIV cascade of care? Results of a population-based survey in Nsanje District, Malawi.

Nolwenn Conan1, Cyrus P Paye1, Reinaldo Ortuno2, Alexander Chijuwa3, Brown Chiwandira4, Eric Goemaere5, Daniela Belen Garone2, Rebecca M Coulborn1, Menard Chihana1, David Maman1.   

Abstract

INTRODUCTION: The Malawi Ministry of Health (MoH) has been in collaboration with Médecins sans Frontières (MSF) to increase access to quality HIV care through decentralization of antiretroviral therapy (ART) diagnosis and treatment from hospital to clinics in Nsanje District since 2011. A population-based household survey was implemented to provide information on HIV prevalence and cascade of care to inform and prioritize community-based HIV interventions in the district.
METHODS: A cross-sectional survey was conducted between September 2016 and January 2017. Using two-stage cluster sampling, eligible adult individuals aged ≥15 years living in the selected households were asked to participate. Participants were interviewed and tested for HIV at home. Those tested HIV-positive had their HIV-RNA viral load (VL) measured, regardless of their ART status. All participants tested HIV-positive at the time of the survey were advised to report their HIV test result to the health facility of their choice that MSF was supported in the district. HIV-RNA VL results were made available in this health facility.
RESULTS: Among 5,315 eligible individuals, 91.1% were included in the survey and accepted an HIV test. The overall prevalence was 12.1% (95% Confidence Interval (CI): 11.2-13.0) and was higher in women than in men: 14.0% versus 9.5%, P<0.001. Overall HIV-positive status awareness was 80.0% (95%CI: 76.4-83.1) and was associated with sex (P<0.05). Linkage to care was 78.0% (95%CI: 74.3-81.2) and participants in care 76.2% (95%CI: 72.4-79.5). ART coverage among participants aware of their HIV-positive status was 95.3% (95%CI: 92.9-96.9) and was not associated with sex (P = 0.55). Viral load suppression among participants on ART was 89.9% (95%CI: 86.6-92.4) and was not statistically different by sex (p = 0.40).
CONCLUSIONS: Despite encouraging results in HIV testing coverage, cascade of care, and UNAIDS targets in Nsanje District, some gap remains in the first 90, specifically among men and young adults. Enhanced community engagement and new strategies of testing, such as index testing, could be implemented to identify those who are still undiagnosed, particularly men and young adults.

Entities:  

Year:  2021        PMID: 33886575     DOI: 10.1371/journal.pone.0248410

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  2 in total

1.  HIV prevalence and associated factors among female sex workers in Ethiopia, east Africa: A cross-sectional study using a respondent-driven sampling technique.

Authors:  Saro Abdella; Meaza Demissie; Alemayehu Worku; Merga Dheresa; Yemane Berhane
Journal:  EClinicalMedicine       Date:  2022-07-01

2.  Facility-based HIV self-testing strategies may substantially and cost-effectively increase the number of men and youth tested for HIV in Malawi: results from an individual-based mathematical model.

Authors:  Brooke E Nichols; Alexandra de Nooy; Mariet Benade; Kelvin Balakasi; Misheck Mphande; Gabriella Rao; Cassidy W Claassen; Shaukat Khan; Christian Stillson; Colin A Russell; Naoko Doi; Kathryn Dovel
Journal:  J Int AIDS Soc       Date:  2022-10       Impact factor: 6.707

  2 in total

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