Alison C Tree1,2, Nicholas J van As3,4. 1. The Royal Marsden NHS Foundation Trust, London, UK. Alison.tree@icr.ac.uk. 2. The Institute of Cancer Research, London, UK. Alison.tree@icr.ac.uk. 3. The Royal Marsden NHS Foundation Trust, London, UK. 4. The Institute of Cancer Research, London, UK.