Literature DB >> 33880952

Retrospective Quality Improvement Study of Insulin-Induced Hypoglycemia and Implementation of Hospital-Wide Initiatives.

Carter Shelton1,2, Andrew P Demidowich3,4, Mahsa Motevalli5, Sam Sokolinsky6, Periwinkle MacKay7, Cynthia Tucker7, Cora Abundo8, Eileen Peters8, Roliette Gooding8, Margaret Hackett8, Joyce Wedler9, Lee Ann Alexander10, Luvenia Barry11, Mary Flynn11, Patricia Rios11, Constance Lulu Fulda12, Michelle F Young12, Barbara Kahl13, Eileen Pummer14, Nestoras N Mathioudakis4, Aniket Sidhaye4, Eric E Howell15, Leo Rotello5, Mihail Zilbermint2,4,5.   

Abstract

BACKGROUND: Hospitalized patients who are receiving antihyperglycemic agents are at increased risk for hypoglycemia. Inpatient hypoglycemia may lead to increased risk for morbidity, mortality, prolonged hospitalization, and readmission within 30 days of discharge, which in turn may lead to increased costs. Hospital-wide initiatives targeting hypoglycemia are known to be beneficial; however, their impact on patient care and economic measures in community nonteaching hospitals are unknown.
METHODS: This retrospective quality improvement study examined the effects of hospital-wide hypoglycemia initiatives on the rates of insulin-induced hypoglycemia in a community hospital setting from January 1, 2016, until September 30, 2019. The potential cost of care savings has been calculated.
RESULTS: Among 49 315 total patient days, 2682 days had an instance of hypoglycemia (5.4%). Mean ± SD hypoglycemic patient days/month was 59.6 ± 16.0. The frequency of hypoglycemia significantly decreased from 7.5% in January 2016 to 3.9% in September 2019 (P = .001). Patients with type 2 diabetes demonstrated a significant decrease in the frequency of hypoglycemia (7.4%-3.8%; P < .0001), while among patients with type 1 diabetes the frequency trended downwards but did not reach statistical significance (18.5%-18.0%; P = 0.08). Based on the reduction of hypoglycemia rates, the hospital had an estimated cost of care savings of $98 635 during the study period.
CONCLUSIONS: In a community hospital setting, implementation of hospital-wide initiatives targeting hypoglycemia resulted in a significant and sustainable decrease in the rate of insulin-induced hypoglycemia. These high-leverage risk reduction strategies may be translated into considerable cost savings and could be implemented at other community hospitals.

Entities:  

Keywords:  community hospital; cost savings; diabetes; hypoglycemia; insulin; insulin-induced

Mesh:

Substances:

Year:  2021        PMID: 33880952      PMCID: PMC8258511          DOI: 10.1177/19322968211008513

Source DB:  PubMed          Journal:  J Diabetes Sci Technol        ISSN: 1932-2968


  31 in total

1.  Intensive versus conventional glucose control in critically ill patients.

Authors:  Simon Finfer; Dean R Chittock; Steve Yu-Shuo Su; Deborah Blair; Denise Foster; Vinay Dhingra; Rinaldo Bellomo; Deborah Cook; Peter Dodek; William R Henderson; Paul C Hébert; Stephane Heritier; Daren K Heyland; Colin McArthur; Ellen McDonald; Imogen Mitchell; John A Myburgh; Robyn Norton; Julie Potter; Bruce G Robinson; Juan J Ronco
Journal:  N Engl J Med       Date:  2009-03-24       Impact factor: 91.245

2.  The clinical endocrinology workforce: current status and future projections of supply and demand.

Authors:  Robert A Vigersky; Lisa Fish; Paul Hogan; Andrew Stewart; Stephanie Kutler; Paul W Ladenson; Michael McDermott; Kenneth H Hupart
Journal:  J Clin Endocrinol Metab       Date:  2014-06-18       Impact factor: 5.958

3.  PREVENTION AND MANAGEMENT OF INSULIN-ASSOCIATED HYPOGLYCEMIA IN HOSPITALIZED PATIENTS.

Authors:  Nestoras Mathioudakis; Estelle Everett; Sherita Hill Golden
Journal:  Endocr Pract       Date:  2016-04-04       Impact factor: 3.443

4.  Inpatient Diabetes Management During the COVID-19 Crisis: Experiences From Two Community Hospitals.

Authors:  Carter Shelton; Andrew P Demidowich; Mihail Zilbermint
Journal:  J Diabetes Sci Technol       Date:  2020-06-02

5.  Financial implications of glycemic control: results of an inpatient diabetes management program.

Authors:  Christopher A Newton; Sandra Young
Journal:  Endocr Pract       Date:  2006 Jul-Aug       Impact factor: 3.443

6.  Impact of endocrine and diabetes team consultation on hospital length of stay for patients with diabetes.

Authors:  C S Levetan; J R Salas; I F Wilets; B Zumoff
Journal:  Am J Med       Date:  1995-07       Impact factor: 4.965

7.  Association between hypoglycemia and inpatient mortality and length of hospital stay in hospitalized, insulin-treated patients.

Authors:  Kimberly G Brodovicz; Vinay Mehta; Qiaoyi Zhang; Changgeng Zhao; Michael J Davies; Jieling Chen; Larry Radican; Samuel S Engel
Journal:  Curr Med Res Opin       Date:  2012-12-14       Impact factor: 2.580

Review 8.  The Financial Impact of an Inpatient Diabetes Management Service.

Authors:  Waqas Zia Haque; Andrew Paul Demidowich; Aniket Sidhaye; Sherita Hill Golden; Mihail Zilbermint
Journal:  Curr Diab Rep       Date:  2021-01-15       Impact factor: 4.810

9.  Response to comment on: Draznin et al. Pathways to quality inpatient management of hyperglycemia and diabetes: a call to action. Diabetes Care 2013;36:1807-1814.

Authors:  Boris Draznin; Janice Gilden; Sherita H Golden; Silvio Inzucchi
Journal:  Diabetes Care       Date:  2013-12       Impact factor: 19.112

10.  Challenges With Insulin in the Inpatient Setting.

Authors:  Denise M Kolanczyk; Rachel C Dobersztyn
Journal:  Diabetes Spectr       Date:  2016-08
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  2 in total

1.  Hospital Diabetes Meeting 2022.

Authors:  Jingtong Huang; Andrea M Yeung; Kevin T Nguyen; Nicole Y Xu; Jean-Charles Preiser; Robert J Rushakoff; Jane Jeffrie Seley; Guillermo E Umpierrez; Amisha Wallia; Andjela T Drincic; Roma Gianchandani; M Cecilia Lansang; Umesh Masharani; Nestoras Mathioudakis; Francisco J Pasquel; Signe Schmidt; Viral N Shah; Elias K Spanakis; Andreas Stuhr; Gerlies M Treiber; David C Klonoff
Journal:  J Diabetes Sci Technol       Date:  2022-07-29

2.  The Endocrine Hospitalist: Enhancing the Quality of Diabetes Care.

Authors:  Mihail Zilbermint
Journal:  J Diabetes Sci Technol       Date:  2021-05-06
  2 in total

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