Juan Wang1, Zhe Yang2, Yan Zheng1, Yaling Peng1, Qing Wang1, Hongli Xia1, Yan Wang1, Jin Ding1, Ping Zhu3, Lei Shang4, Zhaohui Zheng5. 1. Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China. 2. Department of Health Statistics, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China. 3. Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China. zhuping@fmmu.edu.cn. 4. Department of Health Statistics, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China. shanglei@fmmu.edu.cn. 5. Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China. zhengzhimmu@163.com.
Abstract
OBJECTIVES: For patients with rheumatoid arthritis (RA) in China, little is known of how their illness perceptions affect their health-related quality of life (HRQoL). The present study investigated associations between specific illness perceptions due to RA and HRQoL features. METHODS: For 191 patients with RA, illness perceptions were measured using the Brief Illness Perceptions Questionnaire (BIPQ) comprising 8 domains. HRQoL was determined with the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Multivariate linear regression analyses were performed. RESULTS: The overall BIPQ of patients with RA was 49.09 ± 11.06. The highest and lowest scores were for concern (9.15 ± 1.81) and personal control (4.30 ± 2.52), respectively. Multivariate stepwise regression analyses showed that the overall BIPQ was significantly negatively associated with each HRQoL feature, and HRQoL total score (β = - 0.343, P < 0.001, 95% CI - 7.080 to - 4.077). Positive associations between BIPQ features and HRQoL included personal control (β = 0.119, P = 0.004, 95% CI 2.857-14.194) and treatment control (β = 0.084, P = 0.029, 95% CI 0.640-12.391). Negative associations with HRQoL were identity (β = - 0.105, P = 0.034, 95% CI - 13.159 to - 0.430) and emotional response (β = - 0.207, P < 0.001, 95% CI - 18.334 to - 6.811). CONCLUSIONS: Patients with RA in China perceive their illness in ways that affect their HRQoL. These results suggest that strategies that target these perceptions may improve the quality of life of these patients.
OBJECTIVES: For patients with rheumatoid arthritis (RA) in China, little is known of how their illness perceptions affect their health-related quality of life (HRQoL). The present study investigated associations between specific illness perceptions due to RA and HRQoL features. METHODS: For 191 patients with RA, illness perceptions were measured using the Brief Illness Perceptions Questionnaire (BIPQ) comprising 8 domains. HRQoL was determined with the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Multivariate linear regression analyses were performed. RESULTS: The overall BIPQ of patients with RA was 49.09 ± 11.06. The highest and lowest scores were for concern (9.15 ± 1.81) and personal control (4.30 ± 2.52), respectively. Multivariate stepwise regression analyses showed that the overall BIPQ was significantly negatively associated with each HRQoL feature, and HRQoL total score (β = - 0.343, P < 0.001, 95% CI - 7.080 to - 4.077). Positive associations between BIPQ features and HRQoL included personal control (β = 0.119, P = 0.004, 95% CI 2.857-14.194) and treatment control (β = 0.084, P = 0.029, 95% CI 0.640-12.391). Negative associations with HRQoL were identity (β = - 0.105, P = 0.034, 95% CI - 13.159 to - 0.430) and emotional response (β = - 0.207, P < 0.001, 95% CI - 18.334 to - 6.811). CONCLUSIONS:Patients with RA in China perceive their illness in ways that affect their HRQoL. These results suggest that strategies that target these perceptions may improve the quality of life of these patients.
Entities:
Keywords:
Health-related quality of life (HRQoL); Illness perceptions; Rheumatoid arthritis; SF-36
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