| Literature DB >> 33876727 |
Salwa Naushin1, Viren Sardana2, Rajat Ujjainiya1, Nitin Bhatheja2, Rintu Kutum2, Akash Kumar Bhaskar1, Shalini Pradhan1, Satyartha Prakash2, Raju Khan3, Birendra Singh Rawat4, Karthik Bharadwaj Tallapaka5, Mahesh Anumalla5, Giriraj Ratan Chandak5, Amit Lahiri6, Susanta Kar6, Shrikant Ramesh Mulay6, Madhav Nilakanth Mugale6, Mrigank Srivastava6, Shaziya Khan6, Anjali Srivastava6, Bhawana Tomar6, Murugan Veerapandian7, Ganesh Venkatachalam7, Selvamani Raja Vijayakumar7, Ajay Agarwal8, Dinesh Gupta8, Prakash M Halami9, Muthukumar Serva Peddha9, Gopinath M Sundaram9, Ravindra P Veeranna9, Anirban Pal10, Vinay Kumar Agarwal10, Anil Ku Maurya10, Ranvijay Kumar Singh11, Ashok Kumar Raman11, Suresh Kumar Anandasadagopan12, Parimala Karuppanan12, Subramanian Venkatesan12, Harish Kumar Sardana13, Anamika Kothari13, Rishabh Jain13, Anupama Thakur13, Devendra Singh Parihar13, Anas Saifi13, Jasleen Kaur13, Virendra Kumar13, Avinash Mishra14, Iranna Gogeri15, Geethavani Rayasam16, Praveen Singh17, Rahul Chakraborty18, Gaura Chaturvedi17, Pinreddy Karunakar17, Rohit Yadav17, Sunanda Singhmar17, Dayanidhi Singh17, Sharmistha Sarkar17, Purbasha Bhattacharya17, Sundaram Acharya17, Vandana Singh17, Shweta Verma17, Drishti Soni17, Surabhi Seth17, Sakshi Vashisht17, Sarita Thakran17, Firdaus Fatima17, Akash Pratap Singh17, Akanksha Sharma17, Babita Sharma17, Manikandan Subramanian17, Yogendra S Padwad19, Vipin Hallan20, Vikram Patial20, Damanpreet Singh20, Narendra Vijay Tripude20, Partha Chakrabarti21, Sujay Krishna Maity21, Dipyaman Ganguly21, Jit Sarkar21, Sistla Ramakrishna22, Balthu Narender Kumar22, Kiran A Kumar22, Sumit G Gandhi23, Piyush Singh Jamwal23, Rekha Chouhan23, Vijay Lakshmi Jamwal23, Nitika Kapoor23, Debashish Ghosh24, Ghanshyam Thakkar24, Umakanta Subudhi25, Pradip Sen26, Saumya Ray Chaudhury26, Rashmi Kumar26, Pawan Gupta26, Amit Tuli26, Deepak Sharma27, Rajesh P Ringe26, Amarnarayan D28, Mahesh Kulkarni29, Dhansekaran Shanmugam30, Mahesh S Dharne31, Sayed G Dastager31, Rakesh Joshi31, Amita P Patil31, Sachin N Mahajan31, Abujunaid Habib Khan31, Vasudev Wagh31, Rakesh Kumar Yadav31, Ajinkya Khilari31, Mayuri Bhadange31, Arvindkumar H Chaurasiya31, Shabda E Kulsange31, Krishna Khairnar32, Shilpa Paranjape32, Jatin Kalita33, Narahari G Sastry33, Tridip Phukan33, Prasenjit Manna33, Wahengbam Romi33, Pankaj Bharali33, Dibyajyoti Ozah33, Ravi Kumar Sahu33, Elapavalooru Vssk Babu34, Rajeev Sukumaran35, Aiswarya R Nair35, Prajeesh Kooloth Valappil35, Anoop Puthiyamadam35, Adarsh Velayudhanpillai35, Kalpana Chodankar36, Samir Damare36, Yennapu Madhavi37, Ved Varun Aggarwal38, Sumit Dahiya38, Anurag Agrawal39, Debasis Dash40, Shantanu Sengupta1.
Abstract
To understand the spread of SARS-CoV2, in August and September 2020, the Council of Scientific and Industrial Research (India), conducted a sero-survey across its constituent laboratories and centers across India. Of 10,427 volunteers, 1058 (10.14%) tested positive for SARS CoV2 anti-nucleocapsid (anti-NC) antibodies; 95% of which had surrogate neutralization activity. Three-fourth of these recalled no symptoms. Repeat serology tests at 3 (n=607) and 6 (n=175) months showed stable anti-NC antibodies but declining neutralization activity. Local sero-positivity was higher in densely populated cities and was inversely correlated with a 30 day change in regional test positivity rates (TPR). Regional seropositivity above 10% was associated with declining TPR. Personal factors associated with higher odds of sero-positivity were high-exposure work (Odds Ratio, 95% CI, p value; 2∙23, 1∙92-2∙59, <0.0001), use of public transport (1∙79, 1∙43-2∙24, <0.0001), not smoking (1∙52, 1∙16-1∙99, 0∙0257), non-vegetarian diet (1∙67, 1∙41-1∙99, <0.0001), and B blood group (1∙36,1∙15-1∙61, 0∙001).Entities:
Keywords: medicine; viruses
Year: 2021 PMID： 33876727 DOI： 10.7554/eLife.66537
Source DB: PubMed Journal: Elife ISSN： 2050-084X Impact factor: 8.140