Literature DB >> 33876634

Deoxyfluorination of Carboxylic Acids with KF and Highly Electron-Deficient Fluoroarenes.

Siyu Mao1, Jordan H Kramer1, Haoran Sun1.   

Abstract

A deoxyfluorination reaction of carboxylic acids using potassium fluoride (KF) and highly electron-deficient fluoroarenes is reported here, giving acyl fluorides in moderate to excellent yield (57-92% based on NMR integration and 34-95% for isolated examples).

Entities:  

Year:  2021        PMID: 33876634     DOI: 10.1021/acs.joc.0c02491

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Nucleophilic Fluorination Catalyzed by a Cyclometallated Rhodium Complex.

Authors:  Patrick J Morgan; Graham C Saunders; Stuart A Macgregor; Andrew C Marr; Peter Licence
Journal:  Organometallics       Date:  2022-03-31       Impact factor: 3.837

  1 in total

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