| Literature DB >> 33872038 |
Shane S Kelly1,2, Tun-Li Shen1, Ming Xian1.
Abstract
Oxidation of α-siloxy thioethers leads to the formation of the corresponding sulfoxides as unstable intermediates, which undergo an intramolecular oxygen-to-oxygen silyl migration to break the C-S linkage. This process produces silyl protected sulfenic acids and subsequently thiosulfinates. It was used to develop oxidation-triggered allicin donors.Entities:
Year: 2021 PMID： 33872038 DOI： 10.1021/acs.orglett.1c01149
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005