Literature DB >> 33870840

DEL-1: a potential therapeutic target in inflammatory and autoimmune disease?

George Hajishengallis1, Triantafyllos Chavakis2.   

Abstract

Entities:  

Keywords:  DEL-1; autoimmunity; inflammation; inflammation resolution; multiple sclerosis; periodontitis

Mesh：

Year:  2021        PMID： 33870840      PMCID： PMC8405457          DOI： 10.1080/1744666X.2021.1915771

Source DB:  PubMed          Journal:  Expert Rev Clin Immunol        ISSN： 1744-666X            Impact factor:   5.124


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  24 in total

1.  A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.

Authors:  Zhiming Lin; Jin-Xin Bei; Meixin Shen; Qiuxia Li; Zetao Liao; Yanli Zhang; Qing Lv; Qiujing Wei; Hui-Qi Low; Yun-Miao Guo; Shuangyan Cao; Mingcan Yang; Zaiying Hu; Manlong Xu; Xinwei Wang; Yanlin Wei; Li Li; Chao Li; Tianwang Li; Jianlin Huang; Yunfeng Pan; Ou Jin; Yuqiong Wu; Jing Wu; Zishi Guo; Peigen He; Shaoxian Hu; Husheng Wu; Hui Song; Feng Zhan; Shengyun Liu; Guanmin Gao; Zhangsuo Liu; Yinong Li; Changhong Xiao; Juan Li; Zhizhong Ye; Weizhen He; Dongzhou Liu; Lingxun Shen; Anbin Huang; Henglian Wu; Yi Tao; Xieping Pan; Buyun Yu; E Shyong Tai; Yi-Xin Zeng; Ee Chee Ren; Yan Shen; Jianjun Liu; Jieruo Gu
Journal:  Nat Genet       Date:  2011-12-04       Impact factor: 38.330

Review 2.  Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils.

Authors:  Stephen J Galli; Niels Borregaard; Thomas A Wynn
Journal:  Nat Immunol       Date:  2011-10-19       Impact factor: 25.606

3.  DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates.

Authors:  Jieun Shin; Tomoki Maekawa; Toshiharu Abe; Evlambia Hajishengallis; Kavita Hosur; Kalyani Pyaram; Ioannis Mitroulis; Triantafyllos Chavakis; George Hajishengallis
Journal:  Sci Transl Med       Date:  2015-09-30       Impact factor: 17.956

4.  Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.

Authors:  Ioannis Mitroulis; Lan-Sun Chen; Rashim Pal Singh; Ioannis Kourtzelis; Matina Economopoulou; Tetsuhiro Kajikawa; Maria Troullinaki; Athanasios Ziogas; Klara Ruppova; Kavita Hosur; Tomoki Maekawa; Baomei Wang; Pallavi Subramanian; Torsten Tonn; Panayotis Verginis; Malte von Bonin; Manja Wobus; Martin Bornhäuser; Tatyana Grinenko; Marianna Di Scala; Andres Hidalgo; Ben Wielockx; George Hajishengallis; Triantafyllos Chavakis
Journal:  J Clin Invest       Date:  2017-08-28       Impact factor: 14.808

5.  The secreted protein DEL-1 activates a β3 integrin-FAK-ERK1/2-RUNX2 pathway and promotes osteogenic differentiation and bone regeneration.

Authors:  Da-Yo Yuh; Tomoki Maekawa; Xiaofei Li; Tetsuhiro Kajikawa; Khalil Bdeir; Triantafyllos Chavakis; George Hajishengallis
Journal:  J Biol Chem       Date:  2020-04-12       Impact factor: 5.157

6.  Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.

Authors:  Eun Young Choi; Emmanouil Chavakis; Marcus A Czabanka; Harald F Langer; Line Fraemohs; Matina Economopoulou; Ramendra K Kundu; Alessia Orlandi; Ying Yi Zheng; Darue A Prieto; Christie M Ballantyne; Stephanie L Constant; William C Aird; Thalia Papayannopoulou; Carl G Gahmberg; Mark C Udey; Peter Vajkoczy; Thomas Quertermous; Stefanie Dimmeler; Christian Weber; Triantafyllos Chavakis
Journal:  Science       Date:  2008-11-14       Impact factor: 47.728

7.  The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss.

Authors:  Mehmet A Eskan; Ravi Jotwani; Toshiharu Abe; Jindrich Chmelar; Jong-Hyung Lim; Shuang Liang; Paul A Ciero; Jennifer L Krauss; Fenge Li; Martina Rauner; Lorenz C Hofbauer; Eun Young Choi; Kyoung-Jin Chung; Ahmed Hashim; Michael A Curtis; Triantafyllos Chavakis; George Hajishengallis
Journal:  Nat Immunol       Date:  2012-03-25       Impact factor: 25.606

Review 8.  Hematopoietic progenitor cells as integrative hubs for adaptation to and fine-tuning of inflammation.

Authors:  Triantafyllos Chavakis; Ioannis Mitroulis; George Hajishengallis
Journal:  Nat Immunol       Date:  2019-06-18       Impact factor: 25.606

9.  Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination.

Authors:  Eun Young Choi; Jong-Hyung Lim; Ales Neuwirth; Matina Economopoulou; Antonios Chatzigeorgiou; Kyoung-Jin Chung; Stefan Bittner; Seung-Hwan Lee; Harald Langer; Maryna Samus; Hyesoon Kim; Geum-Sil Cho; Tjalf Ziemssen; Khalil Bdeir; Emmanouil Chavakis; Jae-Young Koh; Louis Boon; Kavita Hosur; Stefan R Bornstein; Sven G Meuth; George Hajishengallis; Triantafyllos Chavakis
Journal:  Mol Psychiatry       Date:  2014-11-11       Impact factor: 15.992

10.  Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway.

Authors:  Tomoki Maekawa; Kavita Hosur; Toshiharu Abe; Alpdogan Kantarci; Athanasios Ziogas; Baomei Wang; Thomas E Van Dyke; Triantafyllos Chavakis; George Hajishengallis
Journal:  Nat Commun       Date:  2015-09-16       Impact factor: 14.919
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  1 in total

Review 1.  Osteoimmunology in Periodontitis: Local Proteins and Compounds to Alleviate Periodontitis.

Authors:  Kridtapat Sirisereephap; Tomoki Maekawa; Hikaru Tamura; Takumi Hiyoshi; Hisanori Domon; Toshihito Isono; Yutaka Terao; Takeyasu Maeda; Koichi Tabeta
Journal:  Int J Mol Sci       Date:  2022-05-16       Impact factor: 6.208
  1 in total

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