Literature DB >> 33867901

Explaining Deep Classification of Time-Series Data with Learned Prototypes.

Alan H Gee1,2, Diego Garcia-Olano1,2, Joydeep Ghosh1, David Paydarfar2.   

Abstract

The emergence of deep learning networks raises a need for explainable AI so that users and domain experts can be confident applying them to high-risk decisions. In this paper, we leverage data from the latent space induced by deep learning models to learn stereotypical representations or "prototypes" during training to elucidate the algorithmic decision-making process. We study how leveraging prototypes effect classification decisions of two dimensional time-series data in a few different settings: (1) electrocardiogram (ECG) waveforms to detect clinical bradycardia, a slowing of heart rate, in preterm infants, (2) respiration waveforms to detect apnea of prematurity, and (3) audio waveforms to classify spoken digits. We improve upon existing models by optimizing for increased prototype diversity and robustness, visualize how these prototypes in the latent space are used by the model to distinguish classes, and show that prototypes are capable of learning features on two dimensional time-series data to produce explainable insights during classification tasks. We show that the prototypes are capable of learning real-world features - bradycardia in ECG, apnea in respiration, and articulation in speech - as well as features within sub-classes. Our novel work leverages learned prototypical framework on two dimensional time-series data to produce explainable insights during classification tasks.

Entities:  

Year:  2019        PMID: 33867901      PMCID: PMC8050893     

Source DB:  PubMed          Journal:  CEUR Workshop Proc        ISSN: 1613-0073


  11 in total

1.  PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals.

Authors:  A L Goldberger; L A Amaral; L Glass; J M Hausdorff; P C Ivanov; R G Mark; J E Mietus; G B Moody; C K Peng; H E Stanley
Journal:  Circulation       Date:  2000-06-13       Impact factor: 29.690

Review 2.  Deep learning for healthcare applications based on physiological signals: A review.

Authors:  Oliver Faust; Yuki Hagiwara; Tan Jen Hong; Oh Shu Lih; U Rajendra Acharya
Journal:  Comput Methods Programs Biomed       Date:  2018-04-11       Impact factor: 5.428

3.  Predicting Bradycardia in Preterm Infants Using Point Process Analysis of Heart Rate.

Authors:  Alan H Gee; Riccardo Barbieri; David Paydarfar; Premananda Indic
Journal:  IEEE Trans Biomed Eng       Date:  2016-11-24       Impact factor: 4.538

4.  Cerebral oxygenation during intermittent hypoxemia and bradycardia in preterm infants.

Authors:  Manuel B Schmid; Reinhard J Hopfner; Susanne Lenhof; Helmut D Hummler; Hans Fuchs
Journal:  Neonatology       Date:  2014-12-20       Impact factor: 4.035

5.  Impact of bradycardia on cerebral oxygenation and cerebral blood volume during apnoea in preterm infants.

Authors:  Gerhard Pichler; Berndt Urlesberger; Wilhelm Müller
Journal:  Physiol Meas       Date:  2003-08       Impact factor: 2.833

Review 6.  Forecasting respiratory collapse: theory and practice for averting life-threatening infant apneas.

Authors:  James R Williamson; Daniel W Bliss; David Paydarfar
Journal:  Respir Physiol Neurobiol       Date:  2013-06-02       Impact factor: 1.931

7.  Association Between Intermittent Hypoxemia or Bradycardia and Late Death or Disability in Extremely Preterm Infants.

Authors:  Christian F Poets; Robin S Roberts; Barbara Schmidt; Robin K Whyte; Elizabeth V Asztalos; David Bader; Aida Bairam; Diane Moddemann; Abraham Peliowski; Yacov Rabi; Alfonso Solimano; Harvey Nelson
Journal:  JAMA       Date:  2015-08-11       Impact factor: 56.272

Review 8.  Apnea of prematurity.

Authors:  Richard J Martin; Christopher G Wilson
Journal:  Compr Physiol       Date:  2012-10       Impact factor: 9.090

9.  Arrhythmia detection using deep convolutional neural network with long duration ECG signals.

Authors:  Özal Yıldırım; Paweł Pławiak; Ru-San Tan; U Rajendra Acharya
Journal:  Comput Biol Med       Date:  2018-09-15       Impact factor: 4.589

Review 10.  Cardiorespiratory events in preterm infants: interventions and consequences.

Authors:  J M Di Fiore; C F Poets; E Gauda; R J Martin; P MacFarlane
Journal:  J Perinatol       Date:  2015-11-19       Impact factor: 2.521

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  2 in total

1.  PIP: Pictorial Interpretable Prototype Learning for Time Series Classification.

Authors:  Alireza Ghods; Diane J Cook
Journal:  IEEE Comput Intell Mag       Date:  2022-01-12       Impact factor: 9.809

2.  A Survey of Challenges and Opportunities in Sensing and Analytics for Risk Factors of Cardiovascular Disorders.

Authors:  Nathan C Hurley; Erica S Spatz; Harlan M Krumholz; Roozbeh Jafari; Bobak J Mortazavi
Journal:  ACM Trans Comput Healthc       Date:  2020-12-30
  2 in total

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