Literature DB >> 33865720

Organoids, Where We Stand and Where We Go.

Flaminia Kaluthantrige Don1, Meritxell Huch2.   

Abstract

Organoid cultures hold the promise of transforming basic and clinical research. Here, we provide a storyline of the highlights and breakthroughs that have an impact in present clinical research. We also discuss the bottlenecks that delay their full exploitation for the next generation of biomedical research.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  biomedical applications; bottlenecks; breakthroughs; organoids; stem cells

Mesh:

Year:  2021        PMID: 33865720     DOI: 10.1016/j.molmed.2021.03.001

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN: 1471-4914            Impact factor:   11.951


  3 in total

Review 1.  Forebrain Organoids to Model the Cell Biology of Basal Radial Glia in Neurodevelopmental Disorders and Brain Evolution.

Authors:  Flaminia Kaluthantrige Don; Nereo Kalebic
Journal:  Front Cell Dev Biol       Date:  2022-06-14

2.  Culture of patient-derived multicellular clusters in suspended hydrogel capsules for pre-clinical personalized drug screening.

Authors:  Haijiang Dong; Zequn Li; Suchen Bian; Guangyuan Song; Wenfeng Song; Mingqi Zhang; Haiyang Xie; Shusen Zheng; Xuxu Yang; Tiefeng Li; Penghong Song
Journal:  Bioact Mater       Date:  2022-03-19

3.  Chronic opioid use modulates human enteric microbiota and intestinal barrier integrity.

Authors:  Angélica Cruz-Lebrón; Ramona Johnson; Claire Mazahery; Zach Troyer; Samira Joussef-Piña; Miguel E Quiñones-Mateu; Christopher M Strauch; Stanley L Hazen; Alan D Levine
Journal:  Gut Microbes       Date:  2021 Jan-Dec
  3 in total

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