Bada Yang1, Reem A Mustafa2, Patrick M Bossuyt3, Jan Brozek4, Monica Hultcrantz5, Mariska M G Leeflang3, Holger J Schünemann4, Miranda W Langendam3. 1. Department of Epidemiology and Data Science, Amsterdam University Medical Centers, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands. Electronic address: b.d.yang@outlook.com. 2. Michael G. De Groote Cochrane Canada and McMaster GRADE centres, Department of Health Research Methods, Evidence, and Impact, 1280 Main Street West, McMaster University, Hamilton, Ontario L8S4K1, Canada; Department of Medicine, University of Kansas Medical Center, Kansas City, Kansas, U.S. 3. Department of Epidemiology and Data Science, Amsterdam University Medical Centers, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands. 4. Michael G. De Groote Cochrane Canada and McMaster GRADE centres, Department of Health Research Methods, Evidence, and Impact, 1280 Main Street West, McMaster University, Hamilton, Ontario L8S4K1, Canada; Department of Medicine, 1280 Main Street West, McMaster University, Hamilton, Ontario L8S4K1, Canada. 5. Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU), S:t Eriksgatan 117, SE-102 33, Stockholm, Sweden.
Abstract
OBJECTIVES: This article provides GRADE guidance on how authors of evidence syntheses and health decision makers, including guideline developers, can rate the certainty across a body of evidence for comparative test accuracy questions. STUDY DESIGN AND SETTING: This guidance extends the previously published GRADE guidance for assessing certainty of evidence for test accuracy to scenarios in which two or more index tests are compared. Through an iterative brainstorm-discussion-feedback process within the GRADE working group, we developed a guidance accompanied by practical examples. RESULTS: Rating the certainty of evidence for comparative test accuracy shares many concepts and ideas with the existing GRADE guidance for test accuracy. The rating in comparisons of test accuracy requires additional considerations, such as the selection of appropriate comparative study designs, additional criteria for judging risk of bias, and the consequences of using comparative measures of test accuracy. Distinct approaches to rating certainty are required for comparative test accuracy studies and between-study (indirect) comparisons. CONCLUSION: This GRADE guidance will support transparent assessment of the certainty for a body of comparative test accuracy evidence.
OBJECTIVES: This article provides GRADE guidance on how authors of evidence syntheses and health decision makers, including guideline developers, can rate the certainty across a body of evidence for comparative test accuracy questions. STUDY DESIGN AND SETTING: This guidance extends the previously published GRADE guidance for assessing certainty of evidence for test accuracy to scenarios in which two or more index tests are compared. Through an iterative brainstorm-discussion-feedback process within the GRADE working group, we developed a guidance accompanied by practical examples. RESULTS: Rating the certainty of evidence for comparative test accuracy shares many concepts and ideas with the existing GRADE guidance for test accuracy. The rating in comparisons of test accuracy requires additional considerations, such as the selection of appropriate comparative study designs, additional criteria for judging risk of bias, and the consequences of using comparative measures of test accuracy. Distinct approaches to rating certainty are required for comparative test accuracy studies and between-study (indirect) comparisons. CONCLUSION: This GRADE guidance will support transparent assessment of the certainty for a body of comparative test accuracy evidence.
Authors: Timothy J H Lathlean; Molla M Wassie; Jean M Winter; Rishabh Goyal; Graeme P Young; Erin L Symonds Journal: BMJ Open Date: 2022-05-30 Impact factor: 3.006
Authors: Bin Chen; Ting Yang; Lin Tao; Yuqing Song; Ying Liu; Yan Wang; Lei Xiao; Changxia Xu; Hong Chen Journal: BMJ Open Date: 2022-04-22 Impact factor: 3.006