Hee-Beom Yang1, Jin-Young Min2, Jeik Byun3, Dayoung Ko3, Hyun-Young Kim4, Kyoung-Bok Min5, Sung Eun Jung6. 1. Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea. 2. Institute of Health and Environment, Graduate School of Public Health, Seoul National University, Seoul, Korea. 3. Department of Pediatric Surgery, Seoul National University Children's Hospital, Seoul, Korea. 4. Department of Pediatric Surgery, College of Medicine, Seoul National University, Seoul, Korea. spkhy02@snu.ac.kr. 5. Department of Preventive Medicine, College of Medicine, Seoul National University, Seoul, Korea. minkb@snu.ac.kr. 6. Department of Pediatric Surgery, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
OBJECTIVES: The aim of this study was to investigate the trends of the incidence of and mortality from necrotizing enterocolitis (NEC) in South Korea. METHODS: Claim data were extracted with diagnosis code, including all stage of NEC. Kaplan-Meier curves for cumulative mortality rates are presented by birth weight (Bwt) and gestational age (GA). RESULT: The total number of NEC cases was 5840. The ratio of males to females was 1.2:1. There were 11.9 cases per 10,000 births. There were approximately 10 cases per 1000 preterm births and 50 per 1000 very preterm births. The mortality of patients born under 37 weeks decreased from 38.7% in 2007 to 20.9% in 2017. Male sex, lower GA, and lower Bwt were risk factors for mortality. CONCLUSIONS: NEC incidence and mortality have been decreasing over time in South Korea. Male sex, lower GA, and Bwt were risk factors for mortality.
OBJECTIVES: The aim of this study was to investigate the trends of the incidence of and mortality from necrotizing enterocolitis (NEC) in South Korea. METHODS: Claim data were extracted with diagnosis code, including all stage of NEC. Kaplan-Meier curves for cumulative mortality rates are presented by birth weight (Bwt) and gestational age (GA). RESULT: The total number of NEC cases was 5840. The ratio of males to females was 1.2:1. There were 11.9 cases per 10,000 births. There were approximately 10 cases per 1000 preterm births and 50 per 1000 very preterm births. The mortality of patients born under 37 weeks decreased from 38.7% in 2007 to 20.9% in 2017. Male sex, lower GA, and lower Bwt were risk factors for mortality. CONCLUSIONS: NEC incidence and mortality have been decreasing over time in South Korea. Male sex, lower GA, and Bwt were risk factors for mortality.