Literature DB >> 33861629

GSEAplot: A Package for Customizing Gene Set Enrichment Analysis in R.

Sarah E Innis1, Kelsie Reinaltt1, Mete Civelek1,2, Warren D Anderson2.   

Abstract

Gene Set Enrichment Analysis (GSEA) is used to identify differentially expressed gene sets that are enriched for annotated biological functions. The existing GSEA R code is not in the form of a flexible package with analysis and plotting customization options, and the results produced are not generated in the form of R objects. In this study, we introduce the GSEAplot R package with novel functionality for saving relevant information from the analysis to the current R workspace, and we introduce the ability to customize plots and databases. The GSEAplot package provides a novel utility that facilitates the implementation of GSEA R-based in genomics analysis pipelines.

Entities:  

Keywords:  R package; functional enrichment analysis; gene set analysis

Mesh：

Year:  2021        PMID： 33861629      PMCID： PMC8219183          DOI： 10.1089/cmb.2020.0426

Source DB:  PubMed          Journal:  J Comput Biol        ISSN： 1066-5277            Impact factor:   1.549


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