Literature DB >> 3386067

Flow cytometric DNA analysis of neuroblastoma: correlation with prognostic variables and survival of patients.

H Suzuki1, K Takeuchi.   

Abstract

The DNA ploidy of tumor tissues obtained from 41 patients with neuroblastoma, or ganglioneuroblastoma, which is the histologic variant of neuroblastoma, was determined by flow cytometry. The DNA ploidy was diploid in 7 tumors (5 neuroblastomas and 2 ganglioneuroblastomas) and aneuploid in 34 tumors (20 neuroblastomas and 14 ganglioneuroblastomas). The DNA ploidy of tumor cells did not correlate with the survival of patients and there was no correlation between the DNA ploidy of tumor cells and such prognostic variables, histology, primary site, staging of tumors and operative curability.

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Year:  1988        PMID: 3386067     DOI: 10.1007/bf02470858

Source DB:  PubMed          Journal:  Jpn J Surg        ISSN: 0047-1909


  9 in total

1.  Effect of section thickness on quality of flow cytometric DNA content determinations in paraffin-embedded tissues.

Authors:  R A Stephenson; H Gay; W R Fair; M R Melamed
Journal:  Cytometry       Date:  1986-01

2.  Flow cytometric DNA analysis of neuroblastoma. Correlation with histology and clinical outcome.

Authors:  T Gansler; J Chatten; M Varello; G R Bunin; B Atkinson
Journal:  Cancer       Date:  1986-12-01       Impact factor: 6.860

Review 3.  Flow cytometry in clinical cancer research.

Authors:  B Barlogie; M N Raber; J Schumann; T S Johnson; B Drewinko; D E Swartzendruber; W Göhde; M Andreeff; E J Freireich
Journal:  Cancer Res       Date:  1983-09       Impact factor: 12.701

4.  Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma.

Authors:  A T Look; F A Hayes; R Nitschke; N B McWilliams; A A Green
Journal:  N Engl J Med       Date:  1984-07-26       Impact factor: 91.245

Review 5.  Clinical and biological significance of aneuploidy in human tumours.

Authors:  M L Friedlander; D W Hedley; I W Taylor
Journal:  J Clin Pathol       Date:  1984-09       Impact factor: 3.411

6.  A proposed staging for children with neuroblastoma. Children's cancer study group A.

Authors:  A E Evans; G J D'Angio; J Randolph
Journal:  Cancer       Date:  1971-02       Impact factor: 6.860

7.  Application of DNA flow cytometry to paraffin-embedded archival material for the study of aneuploidy and its clinical significance.

Authors:  D W Hedley; M L Friedlander; I W Taylor
Journal:  Cytometry       Date:  1985-07

8.  [DNA measurement of malignant tumors by impulse cytophotometry. The principles and importance for assessing growth behavior and the degree of abnormality].

Authors:  G E Feichter; K Goerttler; D Haag; J Heep; W W Höpker; M Kaufmann; K L Krämer; F Kubli; W Kühn; S Kunze
Journal:  Dtsch Med Wochenschr       Date:  1984-05-11       Impact factor: 0.628

Review 9.  Clinical application of flow cytometry: a review.

Authors:  O D Laerum; T Farsund
Journal:  Cytometry       Date:  1981-07
  9 in total

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