| Literature DB >> 33858989 |
Benjamin Vernot1, Elena I Zavala1, Asier Gómez-Olivencia2,3,4, Zenobia Jacobs5,6, Viviane Slon1,7,8, Fabrizio Mafessoni1, Frédéric Romagné1, Alice Pearson1, Martin Petr1, Nohemi Sala4,9, Adrián Pablos4,9, Arantza Aranburu2,3, José María Bermúdez de Castro9, Eudald Carbonell10,11, Bo Li5,6, Maciej T Krajcarz12, Andrey I Krivoshapkin13,14, Kseniya A Kolobova13, Maxim B Kozlikin13, Michael V Shunkov13, Anatoly P Derevianko13, Bence Viola15, Steffi Grote1, Elena Essel1, David López Herráez1, Sarah Nagel1, Birgit Nickel1, Julia Richter1, Anna Schmidt1, Benjamin Peter1, Janet Kelso1, Richard G Roberts5,6, Juan-Luis Arsuaga4,16, Matthias Meyer17.
Abstract
Bones and teeth are important sources of Pleistocene hominin DNA, but are rarely recovered at archaeological sites. Mitochondrial DNA has been retrieved from cave sediments, but provides limited value for studying population relationships. We therefore developed methods for the enrichment and analysis of nuclear DNA from sediments, and applied them to cave deposits in western Europe and southern Siberia dated to between approximately 200,000 and 50,000 years ago. We detect a population replacement in northern Spain approximately 100,000 years ago, accompanied by a turnover of mitochondrial DNA. We also identify two radiation events in Neanderthal history during the early part of the Late Pleistocene. Our work lays the ground for studying the population history of ancient hominins from trace amounts of nuclear DNA in sediments.Entities:
Year: 2021 PMID： 33858989 DOI： 10.1126/science.abf1667
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728