Håkan Jarbin1,2, Kristina Höglund1, Gudmundur Skarphedinsson3, Ann Bremander4,5,6,7. 1. Child and Adolescent Psychiatry, Region Halland, Sweden. 2. Department of Clinical Sciences Lund, Lund University, Faculty of Medicine, Child and Adolescent Psychiatry, Lund, Sweden. 3. Faculty of Psychology, University of Iceland, Reykjavik, Iceland. 4. Section of Rheumatology, Department of Clinical Sciences, Lund University, Sweden. 5. Department of Regional Health Research, University of Southern Denmark, Odense, Denmark. 6. Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sonderborg, Denmark. 7. The Rydberg Laboratory for Applied Sciences, Halmstad University, Sweden.
Abstract
AIMS: To assess feasibility and acceptability of exercise in clinically referred adolescents with major depression. METHODS: Outpatients12 to 17 years with mild to moderate persistent depression participated in a supervised, pulse monitored, 14-week aerobic exercise but without control group. Primary outcome was adherence and secondary was clinician-rated Quick Inventory of Depressive Symptomatology - Adolescent (QIDS-A17-C), aerobic capacity, functioning, and well-being. RESULTS: Twenty-one (66%) of 32 eligible adolescents with major depression with disease duration 2.4 (1.1-5.3) years and comorbid ADHD (71%) and anxiety disorders (62%) consented. Estimated maximum heart rate above 70% was achieved for mean 31.6 minutes, indicating that the intensity and duration of the exercise intervention was well received. Fourteen patients (67%) participated throughout the program and attended a median of 29 (81%, range 20-35) supporting satisfaction with the intervention by most patients. QIDS-A17-C score decreased compared to baseline at 15 weeks (p < .001) and further at 1 year (p < .001). Aerobic capacity improved during the intervention but was not maintained, while functioning improved and after 1 year also well-being. CONCLUSION: This 14 week moderate to vigorous aerobic exercise intervention was feasible and well accepted by most adolescents with persistent depression and extensive comorbidities.
AIMS: To assess feasibility and acceptability of exercise in clinically referred adolescents with major depression. METHODS: Outpatients12 to 17 years with mild to moderate persistent depression participated in a supervised, pulse monitored, 14-week aerobic exercise but without control group. Primary outcome was adherence and secondary was clinician-rated Quick Inventory of Depressive Symptomatology - Adolescent (QIDS-A17-C), aerobic capacity, functioning, and well-being. RESULTS: Twenty-one (66%) of 32 eligible adolescents with major depression with disease duration 2.4 (1.1-5.3) years and comorbid ADHD (71%) and anxiety disorders (62%) consented. Estimated maximum heart rate above 70% was achieved for mean 31.6 minutes, indicating that the intensity and duration of the exercise intervention was well received. Fourteen patients (67%) participated throughout the program and attended a median of 29 (81%, range 20-35) supporting satisfaction with the intervention by most patients. QIDS-A17-C score decreased compared to baseline at 15 weeks (p < .001) and further at 1 year (p < .001). Aerobic capacity improved during the intervention but was not maintained, while functioning improved and after 1 year also well-being. CONCLUSION: This 14 week moderate to vigorous aerobic exercise intervention was feasible and well accepted by most adolescents with persistent depression and extensive comorbidities.
Entities:
Keywords:
Adolescent; depression; exercise intervention; persistent depression and comorbidity
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